Alex Smith vs. Buffalo Bills: Alex Smith has provided some lackluster performances over the last three weeks, but that should change this week at home against the Buffalo Bills. Although the Bills are one of the better defenses against opposing quarterbacks, I expect Smith to provide low-end QB1 numbers in this game.
Ben Roethlisberger vs. Green Bay Packers: It’s Roethlisberger at home against a suspect secondary. That means he should be a no-brainer start in this matchup. Don’t be shocked to see him throw for 300 yards and three touchdowns in this game, before ultimately handing over the offense to Le’Veon Bell to close it out.
Dion Lewis vs. Miami Dolphins: It’s the time of year when the Patriots start to find a balance on the offensive side of the ball, and it seems as though Dion Lewis is spear-heading this running attack. Miami is a middle of the pack defense in Fantasy against opposing running backs, but New England will be comfortably ahead for most of this game. Start Lewis with confidence as he should provide RB2 numbers in this game.
Isaiah Crowell @ Cincinnati Bengals: Call it a hunch, but I can see the Browns leaning on Crowell in this matchup against the Bengals. It should be a low-scoring AFC North affair in which Crowell could go for 75 yards and a score. He’s worth a look as a low-end RB2/Flex play this week.
T.Y. Hilton vs. Tennessee Titans: Hilton had only one catch in the previous matchup against the Titans but at home, he tends to shine. The Titans’ secondary still gives up big plays during games and you should see from Hilton in the rematch. Look for him to go over 100 yards and a score in this matchup.
Mohamed Sanu vs. Tampa Bay Buccaneers: With three touchdowns in his last four games, Sanu is taking advantage of the injury that is slowing down Julio Jones. He is seeing single coverage consistently, giving Matt Ryan another option to utilize. With the Buccaneers sporting one of the worst defenses against opposing receivers, this is lining up to be another good game from Sanu.
Charles Clay @ Kansas City Chiefs: In a game in which the Bills will likely be trailing, Tyrod Taylor will be looking to use his security blanket to stay in the ball game. That option is Charles Clay, who should see plenty of targets in this game. He will surely finish Week 12 as a TE1, so get him into your lineup.
Harrison Butker vs. Buffalo Bills: The Chiefs should have plenty of opportunities to score in this game, meaning that Butker could pile up some points in your lineup.
Arizona Cardinals vs. Jacksonville Jaguars: I have a feeling we see the bad Blake Bortles in this game, meaning a number of turnovers, with one potentially going for a score. Plug in the Cardinals defense in this matchup.
Derek Carr vs. Denver Broncos: Derek Carr has only provided two games that were starter-worthy this season, a far cry from last year’s numbers. I don’t expect that to change against the Broncos’ secondary. Look for another option this week.
Josh McCown vs. Carolina Panthers: Josh McCown has been a borderline QB1 all season long, but I don’t expect him to have a good day against the Panthers’ defense. The Panthers are starting to hit on all cylinders, which could make this a nightmarish day for McCown and the Jets.
Frank Gore vs. Tennessee Titans: Week after week Marlon Mack continues to eat into Frank Gore’s workload. I don’t expect Gore to touch the ball enough in this matchup to make a difference.
Adrian Peterson vs. Jacksonville Jaguars: Aside from his first game as a member of the Cardinals, Peterson’s numbers have been very mediocre. He’s getting a lot of touches but not providing much in terms of value. Since he’ll be up against perhaps the best defense in the league, he should be on your bench in Week 12.
Amari Cooper vs. Denver Broncos: Amari Cooper is just not trustworthy enough on a weekly basis to be a starter in this matchup. He’ll likely be covered by Aqib Talib for most of the game, and he could potentially bring in just two catches for the day.
Zay Jones @ Kansas City Chiefs: Kelvin Benjamin is out, Jordan Matthews is iffy at best, so that means Jones should get plenty of targets in this game. Right? Not necessarily. He’ll be shadowed by Marcus Peters and possibly phased out of this game as a result.
Cameron Brate @ Atlanta Falcons: Brate is just not the same player with Ryan Fitzpatrick under center. You can’t trust him in your lineup until Jameis Winston returns.
Mason Crosby vs. Pittsburgh Steelers: The Packers may be lucky to even score in this game, which means you should look elsewhere for a kicker in Week 12.
Los Angeles Rams vs. New Orleans Saints: The Rams have been an up and down fringe starting defense in Fantasy all year. This week they draw a hot Saints offense and should be benched unless you want to take the chance on losing points.