Andrew Luck, IND (shoulder) – Luck has been throwing this week and all reports point to his playing. That said, owners still need to be prepared, as Luck sounded like he would play the last two weeks. It still sounds as though Luck will return in a big-time matchup with the Patriots.
Tyrod Taylor, BUF (knee) – Taylor is a game-time decision for Week 6, although EJ Manuel handled all of the first-team snaps this week. Expect Manuel to start, which downgrades all of the receiving options in Buffalo.
Blake Bortles, JAX (shoulder) – Bortles practiced all week despite a sprained shoulder. The only concern is his pain tolerance As well as he’s been playing (Fantasy wise), he’s a QB1, and Bortles being at quarterback means Allen Robinson and Allen Hurns are high-end WR2s with upside for more.
Josh McCown, CLE (ankle) – McCown was never in serious doubt of missing Week 6, and he’s practiced this week. Nevertheless, a matchup with the Broncos is the best way to see your hot run come to a halt.
Marshawn Lynch, SEA (hamstring) – Lynch practiced Thursday and Friday, which points to his being just fine for this week. Expect Lynch to get back in the lineup and be an immediate RB1. Thomas Rawls should go back to your bench.
Justin Forsett, BAL (ankle) – Forsett practiced Friday and said he’s feeling better than he did early in the week. Owners still need to have a backup plan ready and should have rostered Javorius Allen in case. If Forsett is good to go, he’s a RB1. If he’s out, Allen is a solid RB2 based on volume alone.
Dion Lewis, NE (abdomen) – Lewis practiced in a limited fashion Friday, which doesn’t make this any less murky, especially when it’s the Patriots. We assume Lewis will play, but being a Sunday night game means you need to have backup plans in place, as again, the Patriots could sit him anyway and surprise us all.
LeSean McCoy, BUF (hamstring) – McCoy was supposed to be out until he was 100 percent, but even admitting that he’s not, McCoy is aiming to play. It sounds as if he’ll suit up, and with Karlos Williams out again and the rest of the Bills’ options being quite terrible, McCoy is in line for a decent workload. Still, he is a very risky RB2 with that hamstring.
T.J. Yeldon, JAX (groin) – Yeldon is officially questionable. The problem is that even team reporters have no idea if Yeldon will play despite coach Gus Bradley saying Yeldon didn’t need practice to play but would be a game-time decision. See? Even that isn’t clear. Toby Gerhart and Denard Robinson would step up if Yeldon is out, but neither one is too enticing, especially with Robinson returning from his own injury.
Lions RBs (groin, ankle) – Theo Riddick tweaked his groin and didn’t practice at all on Friday. Joique Bell should play and will get into the mix. However, he’s certainly behind Ameer Abdullah in the talent department and won’t get lead carries. If Riddick is out, Abdullah has nice upside despite his fumbling concerns. Bell is best left out of lineups for at least one more week.
Carlos Hyde, SF (foot) – No real concern here. The 49ers planned to limit Hyde’s practice reps all season, especially with the dings and dents Hyde often has. Reggie Bush is out, setting Hyde up for a big workload.
Odell Beckham, NYG (hamstring) – Uh oh. ODB didn’t practice Friday, or actually at all this week, even though he said he wasn’t worried. The problem is the Giants play Monday night, so you need either to have Dwayne Harris as a backup play, someone on the Eagles or play someone beforehand because you can’t risk the zero.
Rueben Randle, NYG (hamstring) – Randle owners can feel more assured, as he put in a full practice on Friday. If Beckham is out, Randle should see a ton of targets against a weak secondary. He’s a great WR2 if there’s no Beckham and intriguing DFS play… but again, now you’re gambling with Monday night.
Alshon Jeffery, CHI (hamstring) – Jeffery practiced in limited fashion… again. However, it sounds as though Jeffery will actually play this week. Eddie Royal was limited on Friday too and like Jeffery, sounds more likely to play than sit out. You need to monitor both as gametime approaches. Jeffery would be a high-upside WR2 and Royal a WR3/4, and both would see more potential if Martellus Bennett (quad) misses Week 6 – he was a late injury addition on Friday.
Packers WRs (shoulder, hamstring, ankle) – Randall Cobb and James Jones (the first two injuries) are both probable. Cobb was a full practice participant and Jones limited. Neither sounded like they were truly at risk to miss Week 6. Adams however, doesn’t even sound sure himself about playing. Expect Adams to sit out again and get 100 percent healthy over the Packers’ bye in Week 7.
Demaryius Thomas, DEN (neck) – Thomas practiced just fine on Friday after missing Wednesday and Thursday. It was only insurance to make sure Thomas was fine, and Thomas is in line for a big day against the Browns secondary.
T.Y. Hilton, IND (groin) – The Colts added Hilton to their injury report on Thursday, which is normally a bad sign. That said, Hilton returned to practice on Friday, which points him in the right direction along with the probable tag. With Luck back under center, Hilton has WR1 potential again.
Steve Smith, BAL (back) – Smith himself said he doubts he’ll play. Kamar Aiken will be the No. 1 option for the Ravens again but has a tougher matchup this week. The targets should be plentiful though, putting Aiken in WR3 territory as a boom/bust play.
Martavis Bryant, PIT (unknown) – Bryant isn’t on the injury report this week, which means something now that he’s active. The mysterious injury and weird situation from last week aside, Bryant’s upside is capped by Michael Vick at quarterback. As with Aiken, he’s a boom/bust play as a WR3.
Sammy Watkins, BUF (calf) – Watkins is questionable but expected to play. Still, having Manuel at quarterback would severely hinder his upside, even with Percy Harvin questionable as well. Harvin is dealing with a hip issue, and both receivers are no more than WR4s, even WR5s in some leagues.
DeSean Jackson, WSH (hamstring) – DJax left practice early on Thursday, so he is definitely questionable to make his return. Keep tabs, as Jamison Crowder has proven to be a solid WR2 in PPR leagues with Jackson out. If Jackson returns, he’s yet another boom/bust WR3 with Crowder falling back to WR4 value, even in PPR leagues.
Stevie Johnson, SD (hamstring) – Johnson didn’t practice at all and is doubtful. Plan to be without him again this week.
Nelson Agholor, PHI (ankle) – Agholor missed practice Friday, and normally, we don’t worry much about players this low on the Fantasy totem poll. However, his loss presents DFS players with two high risk/reward plays in Josh Huff and Riley Cooper with the Giants secondary banged up (and already terrible).
Jordan Reed, WSH (concussion) – Reed is still in the league’s concussion protocol and is already questionable for Week 7.
Eric Ebron, DET (knee) – Ebron practiced some but just isn’t healthy enough or ready to get back on the field. He’s out again and neither Brandon Pettigrew nor Tim Wright is worth using.
Vernon Davis, SF (knee) – Davis only had limited practice sessions, putting him in the questionable department. You don’t want him anyway, as he’s facing the Ravens.