Phillies vs. Cubs Game Preview: Live MLB Prediction, Odds & Picks
🟢•Next update in: 6 minutes from now
Phillies vs. Cubs preview (Apr 21). Updated every 15 minutes with current odds (Cubs -126), Edmundo Sosa props & pitching matchup: Jesus Luzardo vs. Shota Imanaga (probable).
Today's Data Snapshot
| Market Source: | FanDuel Sportsbook |
|---|---|
| Primary Prediction: | Total U 8.5 |
| Key Player Prop: | Edmundo Sosa Over 0.5 Runs |
| Probable Pitchers: | Jesus Luzardo (LHP; 7.94 ERA) vs. Shota Imanaga (LHP; 2.46 ERA) |



Philadelphia Phillies
8-14
MARQ

Chicago Cubs
13-9

GAME PREDICTIONS
PREDICTED GAME OUTCOME
CHANCE TO WIN
55%
Model Picks
Total
Total U 8.5
Insights provided by the SportsGrid betting model
LATEST PLAYER PROPS
LATEST PLAYER PROPS

PHI

CHC
04/21 ·7:40 PM

Edmundo Sosa
Runs

PHI

CHC
04/21 ·7:40 PM

Edmundo Sosa
RBIs

PHI

CHC
04/21 ·7:40 PM

Nico Hoerner
RBIs
Frequently Asked Questions
What are the latest odds and run line for Philadelphia Phillies vs. Chicago Cubs?
The Chicago Cubs are favored by 1.5 runs on the run line (-1.5), while the Philadelphia Phillies are underdogs +1.5 runs. The moneyline is Philadelphia Phillies +108 and Chicago Cubs -126. The over/under is set at 8.5 runs.
Who is projected to win Philadelphia Phillies vs. Chicago Cubs, and what are the win probabilities?
The model projects the Chicago Cubs to win by 0.4 runs. Win probability is 55% for the Chicago Cubs and 45% for the Philadelphia Phillies.
Who are the probable starting pitchers for Philadelphia Phillies vs. Chicago Cubs?
For this matchup, Philadelphia Phillies is expected to start Jesus Luzardo (LHP; 7.94 ERA), while Chicago Cubs will likely go with Shota Imanaga (LHP; 2.46 ERA). Pitching matchups can change due to injuries, rest days, or strategic decisions.
What are the best bets for Philadelphia Phillies vs. Chicago Cubs (run line, moneyline, total)?
The SportsGrid model's top game pick is Total U 8.5. The projected margin supports this pick.
What are the top player prop picks for Philadelphia Phillies vs. Chicago Cubs?
Top player props include Edmundo Sosa Over 0.5 Runs, Edmundo Sosa Over 0.5 RBIs, Nico Hoerner Over 0.5 RBIs. These are highlighted as strong value plays by the SportsGrid model.




















