John Canady

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Predicted First Loss: at Indiana (Sep. 20)

1) Illinois Fighting Illini

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Predicted First Loss: at Oregon (Oct. 11)

2) Indiana Hoosiers

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Predicted First Loss: at Iowa State (Sep. 6)

3) Iowa Hawkeyes

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Predicted First Loss: at Wisconsin (Sep. 20)

4) Maryland Terrapins

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Predicted First Loss: at Oklahoma (Sep. 6)

5) Michigan Wolverines

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Predicted First Loss: at USC (Sep. 20)

6) Michigan State Spartans

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Predicted First Loss: at Ohio State (Oct. 4)

7) Minnesota Golden Gophers

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Predicted First Loss: vs. Michigan (Sep. 20)

8) Nebraska Cornhuskers

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Predicted First Loss: at Tulane (Aug. 30)

9) Northwestern Wildcats

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Predicted First Loss: vs. Texas (Aug. 30)

10) Ohio State Buckeyes

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Predicted First Loss: at Penn State (Sep. 27)

11) Oregon Ducks

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Predicted First Loss: at Ohio State (Nov. 1)

12) Penn State Nittany Lions

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Predicted First Loss: vs. USC (Sep. 13)

13) Purdue Boilermakers

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Predicted First Loss: vs. Iowa (Sep. 19)

14) Rutgers Scarlet Knights

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Predicted First Loss: vs. Utah (Aug 30)

15) UCLA Bruins

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Predicted First Loss: at Illinois (Sep. 27)

16) USC Trojans

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Predicted First Loss: vs. Ohio State (Sep. 27)

17) Washington Huskies

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Predicted First Loss: at Alabama (Sep. 13)

18) Wisconsin Badgers

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CBS Sports predicts when each Big Ten football team will suffer its first loss of the 2025 regular season, analyzing schedules, matchups, and early challenges.

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