1. Arizona Cardinals @ Los Angeles Rams
After trading Jacoby Brissett and Gardner Minshew's injury, Carson Beck is set to make his NFL debut this Sunday against the Los Angeles Rams. Between Beck making his debut against the Rams and Fernando Mendoza making his debut against the Seahawks, this seems to be the week when rookie QBs are getting thrown right in the fire. The factor of the unknown in the NFL can never be understated. With limited game film, can Beck find holes in a Rams defense that has shown flaws this season? It would be one hell of an introduction to the NFL.