NCAAB · 7 months ago

March Madness 2025: 10 Bracket Busters Set for Cinderella Runs

Grant White

Host · Writer

Midwest Region - (10) Utah State Aggies
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National Championship Odds: +100000

One of several Mountain West teams to be included in the field of 68, the Utah State Aggies aren't on many people's radars. The Aggies make their mark on offense, playing at a deliberate pace with maximum efficiency each time. Not many teams can keep pace when they are on, especially with their proclivity from distance. Utah State will put some distance between itself and its opponents, which could facilitate one of the most unexpected Cinderella runs in this year's tournament.
South Region - (9) Creighton Bluejays
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National Championship Odds: +27000

The South Region of this year's NCAA Tournament bracket is rife with upset potential. Several teams are capable of going on extended runs, including the Creighton Bluejays. Creighton proved their big game acumen in the Big East Tournament, making it all the way to the championship game before bowing out to the St. John's Red Storm. The Bluejays have made it to the Sweet Sixteen in three of the past four tournaments, and another extended run seems plausible this season.
South Region - (12) UC San Diego Tritons
National Championship Odds: +60000

It's easy to lose sight of some of the mid-major conference winners, but the UC San Diego Tritons deserve your attention. The Tritons play a solid two-way game that's conducive to success in the tournament. They have a favorable matchup in the opening round and, depending on how the rest of the region plays out, could have a relatively unobstructed path. Their championship odds are long, but consider the Tritons as upset contenders early in the tourney.
South Region - (14) Lipscomb Bisons: Lipscomb at Kentucky
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National Championship Odds: +100000

No one is giving the Lipscomb Bisons a shot, but we believe in their ability to pull off at least one upset. The Bisons are one of the top shooting teams in March Madness, and the Iowa State Cyclones have been susceptible to that kind of attack. Don't be surprised if the Bisons are playing beyond the opening weekend.
East Region - (6) BYU Cougars
National Championship Odds: +11000

The BYU Cougars are in the daunting East Region but on the gentler half of that bracket. BYU is at its best when pushing the offensive envelope, and that will make a few teams uneasy. We've got the Cougars earmarked for a deep run, and they could be one of the top bracket busters by the end of the tournament.
West Region - (11) Drake Bulldogs
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National Championship Odds: +70000

The Drake Bulldogs are another Cinderella team that could leave a trail of broken hearts in the NCAA Tournament. Drake thrives on defense but can still land a few knockout punches on offense. They will eventually meet their match in the later rounds, but a spot in the Sweet Sixteen is well within their reach.
Midwest Region - (5) Clemson Tigers
National Championship Odds: +11000

Keep an eye on the Clemson Tigers. There is no shortage of playmakers on this squad, and we've seen them rely on different contributors depending on matchups and circumstances. If someone runs cold, there are four other capable starters of picking up the slack. Those in-game adjustments could wreck their opponents' preparation.
Midwest Region - (8) Gonzaga Bulldogs
National Championship Odds: +3800

You can infer from their shorter championship odds that several sharp bettors believe in the Gonzaga Bulldogs. The Zags went on a trip in the West Coast Tournament, and they are a nightmare matchup for some of the top teams in the Midwest. Busting a few brackets seems like an inevitability. Bettors can capitalize with a number of promising plus-money wagers on Gonzaga.
West Region - (4) Maryland Terrapins
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National Championship Odds: +6500

Virtually every year, a Big Ten team comes out of nowhere to shock the college basketball world. While the Maryland Terrapins are a fourth seed, they still check the box as a tournament Cinderella. The Terrapins have an attainable path to the Sweet Sixteen, and a shocking upset wouldn't be out of the question for this top-ranked defense.
South Region - (11) North Carolina Tar Heels
National Championship Odds: +13000

We're calling it now: The North Carolina Tar Heels are this season's sweetheart. Every year, a team comes out of nowhere and captures the country's adoration. With several key contributors playing in their final tournament, we can see the Tar Heels' bandwagon filling up early. Now is the time to lock in any plus-money wagers to ensure maximum value.
Midwest Region - (10) Utah State Aggies
Shoot your shot! Cash in with our four- and five-star College Basketball Picks and buzzer-beating Player Props.

National Championship Odds: +100000

One of several Mountain West teams to be included in the field of 68, the Utah State Aggies aren't on many people's radars. The Aggies make their mark on offense, playing at a deliberate pace with maximum efficiency each time. Not many teams can keep pace when they are on, especially with their proclivity from distance. Utah State will put some distance between itself and its opponents, which could facilitate one of the most unexpected Cinderella runs in this year's tournament.
South Region - (9) Creighton Bluejays
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National Championship Odds: +27000

The South Region of this year's NCAA Tournament bracket is rife with upset potential. Several teams are capable of going on extended runs, including the Creighton Bluejays. Creighton proved their big game acumen in the Big East Tournament, making it all the way to the championship game before bowing out to the St. John's Red Storm. The Bluejays have made it to the Sweet Sixteen in three of the past four tournaments, and another extended run seems plausible this season.

March Madness 2025: 10 Bracket Busters Set for Cinderella Runs

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