Broncos vs Bills Wild Card Predictions | NFL Playoff Picks Today, Best Bets

John Canady
Host · Writer

The Denver Broncos are set to face off against the Buffalo Bills in a wild-card showdown on Saturday. Denver enters this battle with a 10-7 record after barely sneaking in the postseason with a win over the shorthanded Kansas City Chiefs in the regular season finale. Meanwhile, the 13-4 Buffalo Bills are considered genuine contenders to make a run to the Super Bowl as the postseason begins. Nonetheless, against a Sean Payton-coached Broncos squad, the Bills will have their hands full if they hope to advance to the divisional round.
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Broncos vs Bills
- Location: Highmark Stadium (Orchard Park, New York) | Date: Saturday, Jan. 12
- Where to Watch: CBS/Paramount+ | Time: 1:00 PM ET
- Spread: Bills -8.5, Moneyline: Bills -450, Total: 47.5
Broncos vs Bills Best Bet: Broncos +8.5
Buffalo entered this season looking to prove that they would be a force to be reckoned with come January, and they’ve done precisely that. Their opportunity to make a run begins Saturday with Josh Allen playing at an MVP level and Buffalo’s defense showcasing discipline all regular season long. While the Broncos have something to prove of their own, it’ll be hard to trust a rookie quarterback to lead them on the road in a hostile environment to knock off a championship contender like Buffalo. However, while they may not steal a win on the road, it wouldn’t be a shock to see Denver keep the margin of victory less than nine points in this one.
Broncos vs Bills Best Total Bet: Over 47.5
The Broncos head into this game averaging 25 points per game, trailing the Bills, who have consistently looked like one of the top offensive teams in the league, averaging 30.9 points per contest. Expect a dogfight in a game where both teams will be fighting for their seasons to stay alive for one more week. A final score of 34-27 could be a realistic outcome for this matchup.
Broncos Best Player Bet: Bo Nix 2+ Passing Touchdowns +138
Bo Nix has been one of, if not the best, offensive rookies this season. The Oregon product has tossed 29 touchdowns, including two or more in four straight games. With Nix heating up at the right time, the gunslinger could be in line to make a statement in arguably the biggest game of his young career. All things considered, the odds seem safe to bet on Nix to cash in.
Bills Best Player Bet: James Cook to Score 2+ Touchdowns +500
James Cook has emerged as the backfield playmaker that Buffalo has desperately been seeking over the last couple of years. The third-year back finished the season with 1,000+ rushing yards for the second-straight year but elevated his game to another level regarding touchdowns. With 18 touchdowns on the season, Cook is no stranger to the end zone, especially in big games. With how much Buffalo relies on the Georgia alum in both the passing game and rushing attack, the 25-year-old could be in for a monster game on Saturday.
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