NFL DFS: Ranking the Must-Play Defense Matchups for Week 7

Grant White
Host · Writer
1. Cincinnati Bengals
FanDuel Salary: $4,900
Opponent: Cleveland Browns
FanDuel Opponent Rank vs. Position: 29th
The Cleveland Browns are on the verge of collapse, and the Cincinnati Bengals are the beneficiaries in Week 7. We anticipate a strong showing from the Bengals' defense, potentially setting the high mark for fantasy production on Sunday's main slate.
The Bengals defense has been exceptional on the road. In three games away from home, Cincinnati has five takeaways and four sacks, vastly outpacing its home splits. Those metrics will only improve against the Browns, who traded away their best offensive player earlier in the week. Deshaun Watson has also been terrible at protecting the football, throwing three interceptions with five fumbles.
The Battle of Ohio will be one-sided, and we expect Cincinnati's defense to deliver multiple blows. On that basis, they are worth the investment against an underwhelming Browns team.
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5. Tennessee Titans
FanDuel Salary: $3,100
Opponent: Buffalo Bills
FanDuel Opponent Rank vs. Position: 4th
Many DFS punters will prioritize the Buffalo Bills on Sunday, but you can set your roster apart by taking on the Tennessee Titans defense.
Sure, the Titans are terrible. But they would be much worse if not for their stout defensive unit. Tennessee has the top-ranked total defense in the NFL, holding opponents to a paltry 248.8 yards per game, nearly 30 better than the next closest team. We've also seen improved complementary stats, like turnovers and sacks, that could boost their fantasy point production.
The sad truth is the Bills' offense isn't as effective as their output would suggest. Buffalo has been held 309.7 yards per game, 11th-lowest in the NFL. That's unlikely to improve against a fierce Titans' front. This is an unpopular pick, but that isn't always bad in the DFS world.
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4. Minnesota Vikings
FanDuel Salary: $3,900
Opponent: Detroit Lions
FanDuel Opponent Rank vs. Position: 3rd
Heading into Week 7, the Minnesota Vikings have the top fantasy defense in the NFL. The undefeated NFC North leaders are averaging 14.4 fantasy points per game, and that could ratchet even higher in a crucial divisional showdown against the Detroit Lions.
The Vikings are doing everything right. They're averaging 4.0 sacks and 2.6 takeaways per game, second-best in both categories. Moreover, Minnesota has the advantage of playing at home against a Lions squad that will play on the road in back-to-back weeks.
With elite performers in every layer of their defense, the Vikings should deliver where most other teams have failed, containing the Lions' attack. Detroit is primed for regression after last week's near-historic performance, and DFS bettors can benefit by loading up on the Vikings' defense.
3. Los Angeles Rams
FanDuel Salary: $4,100
Opponent: Las Vegas Raiders
FanDuel Opponent Rank vs. Position: 30th
All signs point toward a resounding fantasy performance from the Los Angeles Rams defense in Week 7. Coming off a bye week, Sean McVay will have his team ready to defend against one of the worst offensive teams in the league.
This is as much of a bet against the Las Vegas Raiders as it is on the Rams. The Raiders have turned the ball over more than any other team this season, averaging 2.0 giveaways per game. Likewise, their offensive line has been as sturdy as an umbrella in a hurricane, giving up 3.0 sacks per game.
Fantasy points are ripe for the picking, and the Rams will be ready to reap the rewards on Sunday. They could substantially overproduce relative to their mid-range salary.
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2. San Francisco 49ers
FanDuel Salary: $4,000
Opponent: Kansas City Chiefs
FanDuel Opponent Rank vs. Position: 11th
This game has been circled since the schedule was announced. The San Francisco 49ers host the Kansas City Chiefs in a rematch of Super Bowl LVIII. Revenge will be on the Niners' minds, and we expect them to quell a dangerous Chiefs' offense.
San Francisco is just starting to find its stride. The 49ers defense turned the ball over three times in Week 6 while holding the Seattle Seahawks to 24 points at home. Further, their defensive front has been one of the best at pressuring opposing quarterbacks, totaling 16 sacks across six games.
This is a daunting matchup, but we expect San Francisco to exact revenge for last year's championship defeat. The 49ers should end the day as one of the top-performing defenses.
1. Cincinnati Bengals
FanDuel Salary: $4,900
Opponent: Cleveland Browns
FanDuel Opponent Rank vs. Position: 29th
The Cleveland Browns are on the verge of collapse, and the Cincinnati Bengals are the beneficiaries in Week 7. We anticipate a strong showing from the Bengals' defense, potentially setting the high mark for fantasy production on Sunday's main slate.
The Bengals defense has been exceptional on the road. In three games away from home, Cincinnati has five takeaways and four sacks, vastly outpacing its home splits. Those metrics will only improve against the Browns, who traded away their best offensive player earlier in the week. Deshaun Watson has also been terrible at protecting the football, throwing three interceptions with five fumbles.
The Battle of Ohio will be one-sided, and we expect Cincinnati's defense to deliver multiple blows. On that basis, they are worth the investment against an underwhelming Browns team.
Stay ahead of the game and elevate your sports betting experience with SportsGrid.
5. Tennessee Titans
FanDuel Salary: $3,100
Opponent: Buffalo Bills
FanDuel Opponent Rank vs. Position: 4th
Many DFS punters will prioritize the Buffalo Bills on Sunday, but you can set your roster apart by taking on the Tennessee Titans defense.
Sure, the Titans are terrible. But they would be much worse if not for their stout defensive unit. Tennessee has the top-ranked total defense in the NFL, holding opponents to a paltry 248.8 yards per game, nearly 30 better than the next closest team. We've also seen improved complementary stats, like turnovers and sacks, that could boost their fantasy point production.
The sad truth is the Bills' offense isn't as effective as their output would suggest. Buffalo has been held 309.7 yards per game, 11th-lowest in the NFL. That's unlikely to improve against a fierce Titans' front. This is an unpopular pick, but that isn't always bad in the DFS world.
Tackle the Odds with SportsGrid’s Expert NFL Game Picks and NFL Player Prop Picks.

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