Week 17 NFL Betting Guide: Best Bet, Prop, Predictions for Sunday & Monday Games

We set you up for Week 17 with our NFL Betting Guide.

Week 17 Recaps: Seahawks Top Bears in Low-Scoring Battle | Chiefs Dominate Steelers | Ravens Thump Texans

Saturday, 1:00 p.m. ET: Los Angeles Chargers @ New England Patriots: Preview

• Spread: Chargers -4.5 | Moneyline: Chargers -225 | Total: 43.5
• Where to Watch: NFL Network | Location: Gillette Stadium (Foxborough, MA)

SportsGrid’s Best Bets: Chargers -4.5 (1-Star) | UNDER 43.5 (5-Stars)

SportsGrid’s Predicted Game Outcome: Chargers by 5 points

SportsGrid’s Top Props: Justin Herbert OVER 31.5 Passing Attempts (5-Stars) | Austin Hooper OVER 13.5 Yard Longest Reception (5-Stars)

Saturday, 4:30 p.m. ET: Denver Broncos @ Cincinnati Bengals: Preview

• Spread: Bengals -3 | Moneyline: Bengals -184 | Total: 49.5
• Where to Watch: NFL Network | Location: Paycor Stadium (Cincinnati, OH)

SportsGrid’s Best Bets: Broncos +3 (3-Stars) | Broncos ML (2-Stars, +154) | UNDER 49.5 (5-Stars)

SportsGrid’s Predicted Game Outcome: Bengals by 2 points

SportsGrid’s Top Props: Courtland Sutton Anytime TD (5-Stars, +170) | Tee Higgins First Touchdown (5-Stars, +850)

Saturday, 8:10 p.m. ET: Arizona Cardinals @ Los Angeles Rams: Preview

• Spread: Rams -6.5 | Moneyline: Rams -310 | Total: 47.5
• Where to Watch: NFL Network | Location: Sofi Stadium (Inglewood, CA)

SportsGrid’s Best Bets: Cardinals +6.5 (5-Stars) | OVER 47.5 (4-Stars)

SportsGrid’s Predicted Game Outcome: Rams by 4 points

SportsGrid’s Top Props: Awaiting Props

Sunday, 1:00 p.m. ET: Dallas Cowboys @ Philadelphia Eagles: Preview

• Spread: Eagles -7.5 | Moneyline: Eagles -340 | Total: 38.5
• Where to Watch: FOX | Location: Lincoln Financial Field (Philadelphia, PA)

SportsGrid’s Best Bets: Cowboys +7.5 (1-Star) | OVER 38.5 (4-Stars)

SportsGrid’s Predicted Game Outcome: Eagles by 7 points

SportsGrid’s Top Props: Jake Ferguson OVER 14.5 Yard Longest Reception (5-Stars) | Saquon Barkley First Touchdown (5-Stars, +230)

Sunday, 1:00 p.m. ET: Tennessee Titans @ Jacksonville Jaguars: Preview

• Spread: Jaguars -1.5 | Moneyline: Jaguars -108 | Total: 39.5 
• Where to Watch: CBS | Location: EverBank Stadium (Jacksonville, FL)

SportsGrid’s Best Bets: Titans +1.5 (5-Stars) 

SportsGrid’s Predicted Game Outcome: Titans by 1 point

SportsGrid’s Top Props: Nick Westbrook-Ikhine Anytime TD (5-Stars, +320) | Brian Thomas Jr. First Touchdown (5-Stars, +650)

Sunday, 1:00 p.m. ET: Carolina Panthers @ Tampa Bay Buccaneers: Preview 

• Spread: Buccaneers -8.5 | Moneyline: Buccaneers -820 | Total: 47.5
• Where to Watch: CBS | Location: Raymond James Stadium (Tampa, FL)

SportsGrid’s Best Bets: Panthers +8.5 (5-Stars) | OVER 47.5 (5-Stars)

SportsGrid’s Predicted Game Outcome: Buccaneers by 6 points

SportsGrid’s Top Props: Bryce Young UNDER 32.5 Passing Attempts (5-Stars, +100) | Mike Evans First Touchdown (5-Stars, +550)

Sunday, 1:00 p.m. ET: Indianapolis Colts @ New York Giants: Preview

• Spread: Colts -7.5 | Moneyline: Colts -405 | Total: 40.5
• Where to Watch: FOX | Location: Metlife Stadium (East Rutherford, NJ)

SportsGrid’s Best Bets: Colts -7.5 (5-Stars) | UNDER 40.5 (5-Stars)

SportsGrid’s Predicted Game Outcome: Colts by 10 points

SportsGrid’s Top Props: Anthony Richardson UNDER 26.5 Passing Attempts (5-Stars) | Jonathan Taylor First Touchdown (5-Stars, +350)

Sunday, 1:00 p.m. ET: Las Vegas Raiders @ New Orleans Saints: Preview

• Spread: Raiders -1.5 | Moneyline: Raiders -116 | Total: 37.5
• Where to Watch: FOX | Location: Caesars Superdome (New Orleans, LA)

SportsGrid’s Best Bets: Raiders -1.5 (1-Star) | UNDER 37.5 (5-Stars) 

SportsGrid’s Predicted Game Outcome: Raiders by 2 points

SportsGrid’s Top Props: Awaiting Props

Sunday, 1:00 p.m. ET: New York Jets @ Buffalo Bills: Preview

• Spread: Bills -8.5 | Moneyline: Bills -510 | Total: 46.5
• Where to Watch: CBS | Location: Highmark Stadium (Orchard Park, NY)

SportsGrid’s Best Bets: Bills -8.5 (1-Star) | OVER 46.5 (5-Stars)

SportsGrid’s Predicted Game Outcome: Bills by 9 points

SportsGrid’s Top Props: Davante Adams First Touchdown (5-Stars, +800) | Josh Allen OVER 29.5 Passing Attempts (5-Stars)

Sunday, 4:05 p.m. ET: Miami Dolphins @ Cleveland Browns: Preview

• Spread: Dolphins -6.5 | Moneyline: Dolphins -330 | Total: 39.5
• Where to Watch: CBS | Location: Huntington Bnak Field (Cleveland, OH)

SportsGrid’s Best Bets: Dolphins -6.5 (5-Stars) | UNDER 39.5 (5-Stars)

SportsGrid’s Predicted Game Outcome: Dolphins by 9 points

SportsGrid’s Top Props: Awaiting Props

Sunday, 4:25 p.m. ET: Green Bay Packers @ Minnesota Vikings: Preview

• Spread: Vikings -1.5 | Moneyline: Vikings -112 | Total: 48.5
• Where to Watch: FOX | Location: US Bank Stadium (Minneapolis, MN)

SportsGrid’s Best Bets: Packers +1.5 (4-Stars) | Packers ML (4-Stars)

SportsGrid’s Predicted Game Outcome: Packers by 3 points

SportsGrid’s Top Props: Jordan Love OVER 32.5 Passing Attempts (5-Stars) | Sam Darnold OVER 32.5 Passing Attempts (5-Stars)

Sunday, 8:20 p.m. ET: Atlanta Falcons @ Washington Commanders: Preview

• Spread: Commanders -4.5 | Moneyline: Commanders -210 | Total: 47.5
• Where to Watch: NBC | Location: Northwest Stadium (Landover, MD)

SportsGrid’s Best Bets: Falcons +4.5 (5-Stars) | UNDER 47.5 (4-Stars)

SportsGrid’s Predicted Game Outcome: Commanders by 2 points

SportsGrid’s Top Props: Michael Penix Jr. UNDER 30.5 Passing Attempts (5-Stars) | Terry McLaurin OVER 24.5 Yard Longest Reception

Monday, 8:15 p.m. ET: Detroit Lions @ San Francisco 49ers: Preview

• Spread: Lions -3.5 | Moneyline: Lions -180 | Total: 50.5
• Where to Watch: ESPN | Location: Levi’s Stadium (Santa Clara, CA)

SportsGrid’s Best Bets: Lions -3.5 (5-Stars) | UNDER 50.5 (5-Stars)

SportsGrid’s Predicted Game Outcome: Lions by 6 points

SportsGrid’s Top Props: Amon-Ra St. Brown First Touchdown (5-Stars, +600)

Check out SportsGrid’s NFL game picks and NFL Props Picks all Season Long.

All Odds Courtesy of FanDuel Sportsbook