NCAAB · 5 months ago

March Madness 2025: Top 10 Plus-Money Sweet 16 Futures Bets

Grant White

Host · Writer

West Region - (11) Drake Bulldogs
Odds to Make the Sweet Sixteen: +1040

It's not captured in the betting line, but the Drake Bulldogs can hang with any team on the defensive end of the court. The Bulldogs were incredibly efficient this season, limiting opponents to an average of 59.7 points per game, the second-fewest in the NCAA. Watch them flash those skills as they catch Mizzou and Texas Tech off guard in Rounds 1 and 2.
South Region - (9) Creighton Bluejays
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Odds to Make the Sweet Sixteen: +890

Undoubtedly, the Creighton Bluejays were built for last year. Still, that doesn't preclude them from success in this year's NCAA Tournament. Creighton opens the tourney as short underdogs in a very winnable game versus the Louisville Cardinals. Presumably, they would need to get past the Auburn Tigers in the Round of 32. With how Auburn has been giving away games lately, Creighton presents tremendous value to make the Sweet Sixteen.
South Region - (11) North Carolina Tar Heels
Odds to Make the Sweet Sixteen: +360

It's hard to cheer against the North Carolina Tar Heels. After barely reaching the tournament, UNC easily dispatched the San Diego State Aztecs in their Play-In game. That sets up a showdown versus the Ole Miss Rebels in the Round of 64. From there, they could have an easier-than-anticipated route to the Sweet Sixteen, as the Lipscomb Bisons are live underdogs versus the Iowa State Cyclones. North Carolina could finally be on the magical run everyone is hoping for.
South Region - (4) Texas A&M Aggies
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Odds to Make the Sweet Sixteen: +130

The Texas A&M Aggies are one of the last teams that should be plus-money to make it to the Sweet Sixteen. The Big 12 competitors were ranked in the top 10 ahead of their semifinal loss to the Arizona Wildcats in the conference tournament. Moreover, they will likely be favorites in both of the games they need to win to get to the Sweet Sixteen. Get this price while it lasts, the Aggies are worth it.
South Region - (12) UC San Diego Tritons
Odds to Make the Sweet Sixteen: +360

Backing the UC San Diego Tritons is an ideal play to make for anyone also looking to get a piece of the Texas A&M Aggies. Despite being a 12 seed, the Tritons are just +2.5 underdogs versus the Michigan Wolverines in the opening round of their South Region matchup. UC San Diego can unleash its offense and bully its way into the Round of 32. With two plus-money wagers on the same side of the bracket, bettors have a plethora of hedging opportunities to open the tournament.
East Region - (6) BYU Cougars
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Odds to Make the Sweet Sixteen: +215

While more prominent programs have received all the laudation they deserve for their late-season runs, the BYU Cougars have been left out of the mix. Before their conference tournament loss to the Houston Cougars, BYU was averaging 89.1 points per game. They can easily flex those offensive muscles on the VCU Rams in the opening round, and would have no problem repeating the feat against the Wisconsin Badgers. The Cougars will be part of the March Madness frenzy.
East Region - (12) Liberty Flames

Odds to Make the Sweet Sixteen: +1320

At this point, the NCAA Tournament committee is taunting bettors with their 12 vs. 5 matchups. The Liberty Flames have one of the most underrated defenses in the country but can still put up points on offense. As a result, they will put the Oregon Ducks on upset watch in the opening round and could pull off a stunner in Round 2. Low-key, the best longshot bet on the board.
Midwest Region - (5) Clemson Tigers

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Odds to Make the Sweet Sixteen: +128

The Clemson Tigers can turn to any one of their starters to beat you. All but one of their starters averages north of 11.0 points per game, and all five can hit from distance. That's the type of depth scoring that typically fares well in the big dance, and the Tigers are no exception. Clemson can upend the 12 vs. 5 seed mayhem and push their way past Purdue in the next round.
Midwest Region - (8) Gonzaga Bulldogs
Odds to Make the Sweet Sixteen: +300

At first glance, the Gonzaga Bulldogs' path to the Sweet Sixteen appears obstructed. However, we've seen them hit their stride late in the season. The Zags were easily able to cash as -3.5 chalk in the West Coast Tournament Championship Game, making it nine wins over their last ten. Georgia hasn't been the same team away from home, and the Houston Cougars have fallen victim to elite guards in the past. This is a team everyone should have circled through the opening rounds.
Midwest Region - (10) Utah State Aggies
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Odds to Make the Sweet Sixteen: +980

Several tournament-worthy teams emerged from the Mountain West. While they didn't win the conference tournament, the Utah State Aggies are still the highest-seeded team of the bunch. Utah State has one of the most efficient offenses in the country without compromising on the defensive end. Two upsets are well within reach for the Aggies.
West Region - (11) Drake Bulldogs
Odds to Make the Sweet Sixteen: +1040

It's not captured in the betting line, but the Drake Bulldogs can hang with any team on the defensive end of the court. The Bulldogs were incredibly efficient this season, limiting opponents to an average of 59.7 points per game, the second-fewest in the NCAA. Watch them flash those skills as they catch Mizzou and Texas Tech off guard in Rounds 1 and 2.
South Region - (9) Creighton Bluejays
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Odds to Make the Sweet Sixteen: +890

Undoubtedly, the Creighton Bluejays were built for last year. Still, that doesn't preclude them from success in this year's NCAA Tournament. Creighton opens the tourney as short underdogs in a very winnable game versus the Louisville Cardinals. Presumably, they would need to get past the Auburn Tigers in the Round of 32. With how Auburn has been giving away games lately, Creighton presents tremendous value to make the Sweet Sixteen.