College Football Week 5 Picks: Top 25 Scores & Predictions

(25) BYU Cougars vs. Colorado Buffaloes

• Stadium: Folsom Field
• Location: Boulder, CO
• Time: Saturday 10:15 p.m. ET
• Spread: BYU -6.5 | Total: 47.5
• Moneyline: BYU -260 | Colorado +205

Colorado isn't a pushover in this matchup. BYU battles hard for a win.

Predicted Outcome: BYU 31 - Colorado 28

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(24) TCU Horned Frogs vs. Arizona State Sun Devils

• Stadium: Mountain America Stadium
• Location: Tempe, AZ
• Time: Friday 9:00 p.m. ET
• Spread: Arizona State -2.5 | Total: 55.5
• Moneyline: Arizona State -152 | TCU +126

TCU's time in the Top 25 will be short-lived. Sun Devils cause a ruckus.

Predicted Outcome: Arizona State 28 - TCU 20

(16) Georgia Tech Yellow Jackets vs. Wake Forest Demon Deacons

• Stadium: Allegacy Federal Credit Union Stadium
• Location: Winston-Salem, NC
• Time: Saturday 12:00 p.m. ET
• Spread: Georgia Tech -13.5 | Total: 50.5
• Moneyline: Georgia Tech -610 | Wake Forest +440

Georgia Tech controls the clock for 40 minutes and easily cashes as road chalk.

Predicted Outcome: Georgia Tech 31 - Wake Forest 10

(21) USC Trojans vs. (23) Illinois Fighting Illini

• Stadium: Memorial Stadium
• Location: Champaign, IL
• Time: Saturday 12:00 p.m. ET
• Spread: USC -6.5 | Total: 60.5
• Moneyline: USC -240 | Illinois +195

This is an early start time for a West Coast team. A late surge secures a USC win.

Predicted Outcome: USC 28 - Illinois 27

(22) Notre Dame Fighting Irish vs. Arkansas Razorbacks

• Stadium: Donald W. Reynolds Razorback Stadium
• Location: Fayetteville, AR
• Time: Saturday 12:00 p.m. ET
• Spread: Notre Dame -4.5 | Total: 64.5
• Moneyline: Notre Dame -200 | Arkansas +164

Notre Dame isn't the defensive force it was last year. Arkansas triumphs in the most entertaining game of the weekend.

Predicted Outcome: Arkansas 45 - Notre Dame 40

Utah State Aggies vs. (18) Vanderbilt Commodores

• Stadium: FirstBank Stadium
• Location: Nashville, TN
• Time: Saturday 12:45 p.m. ET
• Spread: Vanderbilt -22.5 | Total: 58.5
• Moneyline: Vanderbilt -2000 | Utah State +980

Vanderbilt still isn't getting the credit it deserves. A convincing win over Utah State doesn't move the needle.

Predicted Outcome: Vanderbilt 42 - Utah State 20

(4) LSU Tigers vs. (13) Ole Miss Rebels

• Stadium: Vaught-Hemingway Stadium
• Location: Oxford, MS
• Time: Saturday 3:30 p.m. ET
• Spread: Ole Miss -1.5 | Total: 54.5
• Moneyline: Ole Miss -122 | LSU +102

Plus-money on the Tigers is a gift. LSU cashes on a late-game score.

Predicted Outcome: LSU 17 - Ole Miss 14

(11) Indiana Hoosiers vs. Iowa Hawkeyes

• Stadium: Kinnick Stadium
• Location: Iowa City, IA
• Time: Saturday 3:30 p.m. ET
• Spread: Indiana -7.5 | Total: 48.5
• Moneyline: Indiana -285 | Iowa +230

Classic letdown spot for the Hoosiers. Iowa is better than advertised.

Predicted Outcome: Iowa 21 - Indiana 17

Auburn Tigers vs. (9) Texas A&M Aggies

• Stadium: Kyle Field
• Location: College Station, TX
• Time: Saturday 3:30 p.m. ET
• Spread: Texas A&M -6.5 | Total: 52.5
• Moneyline: Texas A&M -230 | Auburn +188

Texas A&M is back in the upper echelon. Auburn continues to slide.

Predicted Outcome: Texas A&M 28 - Auburn 20

(1) Ohio State Buckeyes vs. Washington Huskies

• Stadium: Husky Stadium
• Location: Seattle, WA
• Time: Saturday 3:30 p.m. ET
• Spread: Ohio State -8.5 | Total: 51.5
• Moneyline: Ohio State -330 | Washington +260

The Buckeyes are in tough. They won't cover the spread, but their perfect record remains intact.

Predicted Outcome: Ohio State 28 - Washington 24

(15) Tennessee Volunteers vs. Mississippi State Bulldogs

• Stadium: Davis Wade Stadium
• Location: Starkville, MS
• Time: Saturday 4:15 p.m. ET
• Spread: Tennessee -7.5 | Total: 63.5
• Moneyline: Tennessee -310 | Mississippi State +245

Tennessee has something to prove if it wants to get back in the playoff picture.

Predicted Outcome: Tennessee 45 - Mississippi State 17

Arizona Wildcats vs. (14) Iowa State Cyclones

• Stadium: Jack Trice Stadium
• Location: Ames, IA
• Time: Saturday 7:00 p.m. ET
• Spread: Iowa State -6.5 | Total: 48.5
• Moneyline: Iowa State -225 | Arizona +184

Iowa State can't look past Arizona. Low-key one of the best games on the night slate.

Predicted Outcome: Iowa State 24 - Arizona 20

UMass Minutemen vs. (20) Missouri Tigers

• Stadium: Memorial Stadium
• Location: Columbia, MO
• Time: Saturday 7:30 p.m. ET
• Spread: Missouri -44.5 | Total: 56.5
• Moneyline: N/A

Mizzou is ready to roll, but they don't cover even against the lowly Minutemen.

Predicted Outcome: Missouri 48 - UMass 7

(17) Alabama Crimson Tide vs. (5) Georgia Bulldogs

• Stadium: Sanford Stadium
• Location: Athens, GA
• Time: Saturday 7:30 p.m. ET
• Spread: Georgia -2.5 | Total: 52.5
• Moneyline: Georgia -152 | Alabama +126

The current gap between these programs is significantly larger than the betting line suggests. Statement win for Georgia.

Predicted Outcome: Georgia 38 - Alabama 17

(6) Oregon Ducks vs. (3) Penn State Nittany Lions

• Stadium: Beaver Stadium
• Location: University Park, PA
• Time: Saturday 7:30 p.m. ET
• Spread: Penn State -3.5 | Total: 52.5
• Moneyline: Penn State -164 | Oregon +136

This will be a battle, ultimately, with the Nittany Lions prevailing late.

Predicted Outcome: Penn State 28 - Oregon 24

(25) BYU Cougars vs. Colorado Buffaloes

• Stadium: Folsom Field
• Location: Boulder, CO
• Time: Saturday 10:15 p.m. ET
• Spread: BYU -6.5 | Total: 47.5
• Moneyline: BYU -260 | Colorado +205

Colorado isn't a pushover in this matchup. BYU battles hard for a win.

Predicted Outcome: BYU 31 - Colorado 28

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