Week 11 College Football Predictions for All 16 Top 25 Matchups
Grant White
Host · Writer
We are in the stretch drive of the college football season, and Week 11 is loaded with another jaw-dropping slate. Check out our predictions for all 16 Top 25 matchups!
Tulane Green Wave vs (22) Memphis Tigers
- Stadium: Simmons Bank Liberty Stadium
- Location: Memphis, TN
- Time: Friday 9:00 p.m. ET
- Spread: MEM -3.5 | Total: 54.5
- Moneyline: MEM -155 | TULN +135
Memphis wasn’t included in the inaugural CFP rankings. Expect them to come out firing against Tulane.
Predicted Outcome: Memphis 35 – Tulane 27
Northwestern Wildcats vs (19) USC Trojans
- Stadium: Los Angeles Memorial Coliseum
- Location: Los Angeles, CA
- Time: Friday 9:00 p.m. ET
- Spread: USC -14.5 | Total: 50.5
- Moneyline: USC -800 | NW +500
Northwestern might not be able to pull off the outright upset, but this game will be much closer than the betting line implies.
Predicted Outcome: USC 24 – Northwestern 21
(7) BYU Cougars vs (8) Texas Tech Red Raiders
- Stadium: Jones AT&T Stadium
- Location: Lubbock, TX
- Time: Saturday 12:00 p.m. ET
- Spread: TTU -10.5 | Total: 52.5
- Moneyline: TTU -425 | BYU +320
This is Texas Tech’s chance to prove it is the real deal. BYU won’t keep pace offensively.
Predicted Outcome: Texas Tech 34 – BYU 20
(5) Georgia Bulldogs vs Mississippi State Bulldogs
- Stadium: Davis Wade Stadium
- Location: Starkville, MS
- Time: Saturday 12:00 p.m. ET
- Spread: UGA -9.5 | Total: 56.5
- Moneyline: UGA -340 | MSST +270
Mississippi State could have another upset in its crosshairs. Georgia barely cashes on a late-game drive.
Predicted Outcome: Georgia 28 – Mississippi State Bulldogs 25
(2) Indiana Hoosiers vs Penn State Nittany Lions
- Stadium: Beaver Stadium
- Location: University Park
- Time: Saturday 12:00 p.m. ET
- Spread: IND -14.5 | Total: 48.5
- Moneyline: IND -800 | PENN +500
This could upset the entire balance of college football. We’re calling Penn State with the massive upset at Beaver Stadium.
Predicted Outcome: Penn State 24 – Indiana 23
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(1) Ohio State Buckeyes vs Purdue Boilermakers
- Stadium: Ross-Ade Stadium
- Location: West Lafayette, IN
- Time: Saturday 1:00 p.m. ET
- Spread: OSU -30.5 | Total: 47.5
- Moneyline: OSU -20000 | PUR +3000
This number is beyond Ohio State’s reach. Still, a convincing win nonetheless.
Predicted Outcome: Ohio State Buckeyes 31 – Purdue 7
The Citadel Bulldogs vs (6) Ole Miss Rebels
- Stadium: Vaught-Hemingway Stadium
- Location: Oxford, MS
- Time: Saturday 1:00 p.m. ET
- Spread: N/A | Total: N/A
- Moneyline: N/A
Whatever this line opens at, back the Rebels.
Predicted Outcome: Ole Miss 66 – The Citadel 3
(9) Oregon Ducks vs (20) Iowa Hawkeyes
- Stadium: Kinnick Stadium
- Location: Iowa City, IA
- Time: Saturday 3:30 p.m. ET
- Spread: ORE -6.5 | Total: 40.5
- Moneyline: ORE -225 | IOWA +190
This total implies that Iowa will be ready to play, making it hard for Oregon to cover the number.
Predicted Outcome: Oregon 21 – Iowa 18
(3) Texas A&M Aggies vs (22) Missouri Tigers
- Stadium: Faurot Field
- Location: Columbia, MO
- Time: Saturday 3:30 p.m. ET
- Spread: TA&M -6.5 | Total: 47.5
- Moneyline: TA&M -230 | MIZZ +195
Texas A&M’s perfect run comes to an end in Week 11. Missouri keeps its playoff hopes alive.
Predicted Outcome: Missouri 24 – Texas A&M 23
Syracuse Orange vs (18) Miami (FL) Hurricanes
- Stadium: Hard Rock Stadium
- Location: Miami Gardens, FL
- Time: Saturday 3:30 p.m. ET
- Spread: MIA -28.5 | Total: 45.5
- Moneyline: MIA -20000 | SYR +3000
Miami is hanging on by a thread. Thankfully, Syracuse cut loose weeks ago.
Predicted Outcome: Miami 42 – Syracuse 10
Auburn Tigers vs (16) Vanderbilt Commodores
- Stadium: FirstBank Stadium
- Location: Nashville, TN
- Time: Saturday 4:00 p.m. ET
- Spread: VAN -6.5 | Total: 45.5
- Moneyline: VAN -240 | AUB +200
No way this SEC clash goes over the total. Vandy breaks free in the second half to cover.
Predicted Outcome: Vanderbilt 22 – Auburn 15
(23) Washington Huskies vs Wisconsin Badgers
- Stadium: Camp Randall Stadium
- Location: Madison, WI
- Time: Saturday 4:30 p.m. ET
- Spread: WASH -10.5 | Total: 44.5
- Moneyline: WASH -500 | WISC +360
At this point, it’s time to auto-bet against Wisconsin. Washington still won’t get the credit it deserves.
Predicted Outcome: Washington 20 – Wisconsin 7
California Golden Bears vs (15) Louisville Cardinals
- Stadium: L&N Federal Credit Union Stadium
- Location: Louisville, KY
- Time: Saturday 7:00 p.m. ET
- Spread: LOU -20.5 | Total: 50.5
- Moneyline: LOU -1800 | CAL +900
Cal doesn’t travel well. Louisville cruises but falls short of the number.
Predicted Outcome: Louisville 34 – California 14
Wake Forest Demon Deacons vs (14) Virginia Cavaliers
- Stadium: Scott Stadium
- Location: Charlottesville, VA
- Time: Saturday 7:00 p.m. ET
- Spread: UVA -6.5 | Total: 47.5
- Moneyline: UVA -240 | WAKE +200
Wake Forest puts forth a valiant effort, but this has Virginia win/cover written all over it.
Predicted Outcome: Virginia 27 – Wake Forest 20
Navy Midshipmen vs (10) Notre Dame Fighting Irish
- Stadium: Notre Dame Stadium
- Location: South Bend, IN
- Time: Saturday 7:30 p.m. ET
- Spread: ND -25.5 | Total: 55.5
- Moneyline: ND -5000 | NAVY +1500
Notre Dame gets caught sleeping early, but still finds a way to win in the latter stages of the contest.
Predicted Outcome: Notre Dame 31 – Navy 17
LSU Tigers vs (4) Alabama Crimson Tide
- Stadium: Bryant-Denny Stadium
- Location: Tuscaloosa, AL
- Time: Saturday 7:30 p.m. ET
- Spread: ALA -9.5 | Total: 50.5
- Moneyline: ALA -340 | LSU +270
Alabama absolutely annihilates LSU in this spot. It’s not even close.
Predicted Outcome: Alabama 35 – LSU 10
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