Where to Watch Every March Madness 2nd Round Game on Saturday

The second round of March Madness gets underway on Saturday, March 22, with thrilling matchups across the NCAA Tournament. Whether you’re following your bracket or looking for the best bets, here’s where you can watch each game, along with betting odds from Bet365.

Unleash AI power on your March Madness picks. Try our Bracket Pick’em Tool now!

March Madness Central

Region Previews: East | South | West | Midwest

4-5 Star Bets: Game Picks | Props Picks 

(12) McNeese State vs. (4) Purdue Odds at Bet365

-When: 12:10 p.m. ET – Saturday, March 22

-Spread: McNeese State +5.5 (-110) | Purdue -5.5 (-110)

-Moneyline: McNeese State +200 | Purdue -245

-Total: Over 143.0 (-110) | Under 143.0 (-110)

-TV: CBS

-Streaming: Paramount+, Sling TV, Hulu + Live TV

-Follow: SportsGrid App (Download Here)

BET365 PROMO CODE – FIRST BET SAFETY NET $1000 IN BONUS BETS

(10) Arkansas vs. (2) St. John’s Odds at Bet365

-When: 12:40 p.m. ET – Saturday, March 22

-Spread: Arkansas +7.0 (-110) | St. John’s -7.0 (-110)

-Moneyline: Arkansas +240 | St. John’s -300

-Total: Over 144.0 (-110) | Under 144.0 (-110)

-TV: CBS

-Streaming: Paramount+, Sling TV, Hulu + Live TV

-Follow: SportsGrid App (Download Here)

NCAA Tournament Bracket Busters: Top 10 First-Round Most Likely Upsets

(5) Michigan vs. (4) Texas A&M Odds at Bet365

-When: 5:15 p.m. ET – Saturday, March 22

-Spread: Michigan +2.5 (-110) | Texas A&M -2.5 (-110)

-Moneyline: Michigan +125 | Texas A&M -150

-Total: Over 141.0 (-110) | Under 141.0 (-110)

-TV: CBS

-Streaming: Paramount+, Sling TV, Hulu + Live TV

-Follow: SportsGrid App (Download Here)

Shoot your shot! Cash in with our four- and five-star College Basketball Picks and buzzer-beating Player Props.

(11) Drake vs. (3) Texas Tech Odds at Bet365

-When: 6:10 p.m. ET – Saturday, March 22

-Spread: Drake +7.5 (-110) | Texas Tech -7.5 (-110)

-Moneyline: Drake +265 | Texas Tech -330

-Total: Over 127.0 (-110) | Under 127.0 (-110)

-TV: TNT

-Streaming: Max, Sling TV, Hulu + Live TV

-Follow: SportsGrid App (Download Here)

March Madness 2025: Top 10 Plus-Money Sweet 16 Futures Bets

(9) Creighton vs. (1) Auburn Odds at Bet365

-When: 7:10 p.m. ET – Saturday, March 22

-Spread: Creighton +9.0 (-105) | Auburn -9.0 (-115)

-Moneyline: Creighton +350 | Auburn -450

-Total: Over 151.0 (-110) | Under 151.0 (-110)

-TV: TBS

-Streaming: Max, Sling TV, Hulu + Live TV

-Follow: SportsGrid App (Download Here)

March Madness 2025: 10 Bracket Busters Set for Cinderella Runs

(6) BYU vs. (3) Wisconsin Odds at Bet365

-When: 7:45 p.m. ET – Saturday, March 22

-Spread: BYU +1.0 (-110) | Wisconsin -1.0 (-110)

-Moneyline: BYU -105 | Wisconsin -115

-Total: Over 155.0 (-110) | Under 155.0 (-110)

-TV: CBS

-Streaming: Paramount+, Sling TV, Hulu + Live TV

-Follow: SportsGrid App (Download Here)

March Madness 2025: The Top 10 Dream Matchups We Want

(8) Gonzaga vs. (1) Houston Odds at Bet365

-When: 8:40 p.m. ET – Saturday, March 22

-Spread: Gonzaga +5.0 (-110) | Houston -5.0 (-110)

-Moneyline: Gonzaga +185 | Houston -225

-Total: Over 139.5 (-110) | Under 139.5 (-110)

-TV: TNT

-Streaming: Max, Sling TV, Hulu + Live TV

-Follow: SportsGrid App (Download Here)

Top 10 Must-See March Madness First-Round Matchups

(7) UCLA vs. (2) Tennessee Odds at Bet365

-When: 9:40 p.m. ET – Saturday, March 22

-Spread: UCLA +4.5 (-110) | Tennessee -4.5 (-110)

-Moneyline: UCLA +165 | Tennessee -200

-Total: Over 132.5 (-110) | Under 132.5 (-110)

-TV: TBS

-Streaming: Max, Sling TV, Hulu + Live TV

-Follow: SportsGrid App (Download Here)

March Madness 2025: Top 10 Cinderella Final Four Bracket Busters

With an action-packed lineup of second-round March Madness games, fans have multiple ways to watch—via CBS, TNT, TBS, truTV, and top streaming services. Whether following your bracket or looking for betting value, this NCAA Tournament slate delivers elite competition. Don’t miss a minute!

Odds Subject to Change. Get the Latest Game Odds Here.