Chiefs vs Bills Week 11 Predictions | NFL Picks Today, Best Bets

Zack Cook
Host · Writer
In Week 11 of the NFL regular season, the Buffalo Bills are set to host the Kansas City Chiefs on Sunday afternoon. SportsGrid Previews the matchup here.
Where to Watch Chiefs vs Bills
- Location: Highmark Stadium in Orchard Park, New York
- Time: 4:25 p.m. ET | Where to Watch: CBS
- Spread: Bills -2.5 | Moneyline: Bills -132 | Total: 46.5
Chiefs vs Bills Best Bet ATS: Bills -2.5 (-105)
Giving Patrick Mahomes and the Chiefs points in a big game is always dangerous. That’s exactly what the oddsmakers have done for this clash, and it was somewhat expected as a pick ’em, with the Bills laying points due to home-field advantage. The Bills have proven during the regular season that they have the recipe to unravel the Chiefs. Buffalo’s posted a 3-1 record over their last four regular-season games against Kansas City. Yes, the playoffs are a different story, but this isn’t the postseason. The Chiefs enter this clash undefeated but have hardly played perfect football. That’s the sign of a scary and good team, but the Bills are right there with them in the AFC. A win would land the Bills just one game behind the Chiefs in the lost column, making the AFC playoff picture even more interesting. Give me Josh Allen at home against a Kansas City team with much to improve.
Check out SportsGrid’s models NFL Best Bets here.
Chiefs vs Bills Best Bet Total: UNDER 46.5 (-112)
Including the playoffs, the Chiefs and Bills have met six times since 2021. These teams have developed a real rivalry, even if the Chiefs have won the matchups where they count the most. The scoring in these matchups has been mixed. We know there’s plenty of offensive talent on both contenders. Still, two of the last three clashes have landed under the number, and I like that trend to continue on Sunday. The Chiefs have been dominant at stopping the run, while Kansas City’s offense hasn’t done anything that should inspire you to expect them to put up big numbers on the road. Combine that with a Buffalo defensive scheme that can give Kansas City trouble, and this screams under.
Stay ahead of the game and elevate your sports betting experience with SportsGrid.














