10 Bold Predictions for Week 10 of College Football
TJ Inman
Host · Writer
By the time action kicks off on Saturday, the calendar will have turned to November, and we will be in the “business end" of the 2025 college football season. Week 10 is an exciting slate with huge games all day. Here are some bold predictions!
1. Tulane Enters the G5 CFP Conversation
Jon Sumrall’s Tulane Green Wave are 6-1 and 3-0 in the American, and they’ll throw their hat into the ring as a contender for the Group of Five’s College Football Playoff spot with a win on Thursday night against the UTSA Roadrunners. The Green Wave has a lopsided loss at Ole Miss, and they don’t have the quality to compete against whichever team ends up as the five-seed, but the loss by South Florida to Memphis has thrown this race into chaos. The Green Wave has back-to-back road trips (UTSA and then at Memphis) that will go a long way toward determining who will get the G5 playoff bid. They’ll announce themselves as a contender with a resounding win on Thursday night.
Week 10: Tulane (-4.5) at UTSA
2. Texas Loses at Home to Vanderbilt
The Texas Longhorns got just 68 yards on 21 carries from their running backs against a dreadful Mississippi State rush defense, and the offensive line somehow managed to give up 12 tackles for loss against the Bulldogs. That is an alarming number, but it continues a trend for the Texas offensive line and is another sign that the line just isn’t good enough in Austin this season. Vanderbilt is excellent against the run, and their offense is due to bounce back after a rough game against Missouri. The Commodores go to Austin and get a big win that eliminates Texas from postseason discussions and stamps Vandy as a legit SEC contender.
Week 10: Vanderbilt at Texas (-2.5)
3. Duke Beats Clemson in Death Valley
The Duke Blue Devils hit the road after a bye week, and they travel to Clemson as underdogs. The Blue Devils are 4-3 but 3-1 in the ACC and still have an outside shot at reaching the ACC Championship Game. The Clemson Tigers are suffering through their worst season in a long time, and while there is a chance they used their bye week to rally and fix several of their flaws, I consider it far more likely that Dabo Swinney’s squad has checked out. That gives Duke plenty to take advantage of, as the Tigers were most recently seen giving up 35 points to the SMU Mustangs. Duke throws for at least 300 yards, and the Blue Devils win in Death Valley.
Week 10: Duke at Clemson (-3.5)
4. Navy and North Texas Combine for 70+ Points
This is one of my favorite games of the weekend. The matchup between the Navy Midshipmen and North Texas Mean Green will be an extremely entertaining shootout with two high-powered offenses. Navy is unbeaten, and they are averaging 293.8 rushing yards per game (most in the country) and 463.8 total yards per game (15th in the country). On the other sideline, North Texas is third in the country with 501 total yards per game. Look at Navy’s recent scorelines: 34-31 over Air Force, 32-31 against Temple, and 42-32 against Florida Atlantic. North Texas gave up 38 to Army, 22 to South Alabama, 63 to South Florida, and 20 to Charlotte. Bet big on this game going well over the total!
Week 10: Navy at North Texas (-6.5) | Total of 65.5
5. Kansas State Stuns Texas Tech in Manhattan
The Kansas State Wildcats began the season with a loss to Iowa State in Dublin and then returned home and survived a scare against North Dakota, 38-35. There was a thought that they would look more like the team many had expected after getting some rest, but they lost to Army and Arizona and looked like a team far from competitive. After being left for dead, the Wildcats have responded by winning three of four games, with the lone defeat being by one point at Baylor. The two most recent contests were their best of the season as they beat TCU 41-28 and dominated Kansas 42-17. Avery Johnson is playing much better than he did to start the season, and head coach Chris Klieman appears to have figured out how to reach this team. They now host Texas Tech, but the Red Raiders have some concerns at quarterback. Kansas State continues to play well and upsets Texas Tech, all but ending the Red Raiders’ College Football Playoff hopes.
Week 10: Texas Tech (-7.5) at Kansas State
6. Mississippi State Gets 1st SEC Win for Lebby
The Mississippi State Bulldogs have been snake-bitten under head coach Jeff Lebby. The Bulldogs continue to compete but keep dropping close games. This past weekend was the most gut-wrenching of the bunch as they surrendered a three-score lead in the game’s final ten minutes and fell to the Texas Longhorns. This weekend might be their final chance to break the winless streak in the SEC. I believe this team is still fighting for Lebby, and I can’t really say the same about Arkansas under interim coach Bobby Petrino. The Razorbacks collapsed down the stretch against Auburn, and it felt like the final straw for a team that had already fired its head coach. The atmosphere in Fayetteville will not be raucous, and Mississippi State will roll in and finally close out a conference win for Lebby.
Week 10: Mississippi State at Arkansas (-4.5)
7. San Diego State Gets Another Shutout
The San Diego State Aztecs have one of the country’s best defenses. Outside of a confusing 36-13 loss to Washington State, the Aztecs have not surrendered more than 24 points in any game this season. More impressively, they have three separate shutouts, including one in their last outing against Fresno State. San Diego State now hosts the Wyoming Cowboys, a conference foe sitting at 4-4 and 2-2 in the Mountain West. Wyoming scored 28 points against Colorado State with an interim coach, and they’ve scored 28 against San Jose State, but this is not a great offense. The Aztecs rack up their fourth shutout and improve to 4-0 in the Mountain West Conference.
Week 10: Wyoming at San Diego State (-10.5)
8. Tennessee Turns Up Venables’ Hot Seat
Florida is now without a head coach. The LSU job is on the market. UCLA, Arkansas, Penn State, Virginia Tech, and several others are also open. Now, more than ever, schools are looking at the success others are having and are refusing to show any patience. The Oklahoma Sooners had a promising start to the season, but an injury to John Mateer brought in some concern and losses to Texas, and now Ole Miss has put Oklahoma’s back against the wall. They now face another two-loss team, Tennessee, as their challenging schedule continues. A third loss for Oklahoma is going to all but guarantee that they do not reach the College Football Playoff, which will turn up the heat on Brent Venables. Peak ahead at the other three games on their schedule: at Alabama, vs. Missouri, and vs. LSU. Things are going to get very dicey, very quickly, for Venables, and it will really start to be discussed after Tennessee beats them by 10+ points on Saturday.
Week 10: Oklahoma at Tennessee (-3.5)
9. Wake Forest Prolongs FSU’s ACC Losing Streak
The Florida State Seminoles began the season 3-0, but as soon as they entered ACC play, things fell apart. The Seminoles have dropped four straight games, and their conference losing streak now stands at nine. The most recent ACC victory for Mike Norvell’s team was on September 21, 2024, against California. If you take that 14-9 win out, FSU is 1-11 in their last 12 conference games. They’ve had a bye week to figure things out, but I don’t trust Norvell to get this team to buy back in. They now host an undermanned but very well-coached Wake Forest team. The Demon Deacons have won three straight games, including an impressive 13-12 victory over SMU last week. Florida State cannot be trusted, and Wake Forest prolongs their misery, handing the Seminoles a tenth-straight ACC defeat.
Week 10: Wake Forest at Florida State (-8.5)
10. Utah Ends Cincinnati’s Winning Streak
The Cincinnati Bearcats have been very impressive this season. Scott Satterfield’s team has won seven straight games after losing by a field goal in the season-opener to Nebraska. The only two road wins in that stretch have been a 37-34 victory over Kansas and a 49-17 win over the dreadful Oklahoma State Cowboys. They face an entirely different test this Saturday night as they travel to Utah to play the No. 24 Utah Utes. Utah turned to freshman quarterback Byrd Ficklin, and he was awesome in his first start against Colorado. Ficklin had 140 passing yards and 151 rushing yards with three total touchdowns. The whole team responded with an excellent performance, outgaining Colorado 587 yards to 140. The Utes end the Bearcats’ seven-game streak with an impressive win in Salt Lake City and another good outing from Ficklin.
Week 10: Cincinnati at Utah (-7.5)
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