College Football Odds Week 3: Biggest NCAAF Spreads This Week

John David Yonke

The college football season rumbles on with another full slate of games prepared for Week 3. That means there’s a plentiful amount of betting lines on the board for this week’s action.
According to BetMGM Sportsbook’s college football odds, here are the biggest spreads this week.
College Football Odds Week 3: Biggest NCAAF Spreads This Week
Rank | Matchup | Spread |
1 | Bowling Green at Michigan | Michigan -39.5 |
2 | Hawaii at Oregon | Oregon -37.5 |
3 | Central Michigan at Notre Dame | Notre Dame -33.5 |
4 | Alabama at South Florida | Alabama -32.5 |
5 | UL Monroe at Texas A&M | Texas A&M -31.5 |
T6 | Florida State at Boston College | Florida State -28.5 |
T6 | Wyoming at Texas | Texas – 28.5 |
T6 | Kansas at Nevada | Kansas -28.5 |
9 | Western Kentucky at Ohio State | Ohio State -27.5 |
T10 | South Carolina at Georgia | Georgia -26.5 |
T10 | Western Michigan at Iowa | Iowa -26.5 |
T10 | Oklahoma at Tulsa | Oklahoma -26.5 |
1. Bowling Green at Michigan (-39.5)
The Michigan Wolverines (2-0) have been heavily favored in each of their first two contests but have sleepwalked to victories over the East Carolina Pirates (30-3) and UNLV Rebels (35-7). This is the most lopsided matchup yet as offensive coordinator Sherrone Moore fills in as acting head coach.
2. Hawaii at Oregon (-37.5)
For all of the excitement that Timmy Chang’s Run and Shoot has brought to the Hawaii Rainbow Warriors (1-2), their lone win came against an FCS school, and they came up empty-handed in two winnable games against Power 5 teams. They’re likely to get boat raced by an Oregon Ducks (2-0) team that will expect to score every time it has the ball, with Heisman contender Bo Nix leading the charge.
3. Central Michigan at Notre Dame (-33.5)
Jim McElwain’s Central Michigan Chippewas (1-1) needed a last-second 47-yard field goal to get past an FCS team last week, so it should come as no surprise that they’re heavy underdogs against the Notre Dame Fighting Irish (3-0). Sam Hartman leads an offense averaging 8.0 yards per play, while the defense suffocates opponents, limiting them to 3.5 yards per play.
4. Alabama (-32.5) at South Florida
Where does Nick Saban go after losing 34-24 to the Texas Longhorns in Week 2? The answer to that question won’t be found in Week 3 as the Alabama Crimson Tide (1-1) will roll over the poor South Florida Bulls (1-1) in a mismatch.
5. UL Monroe at Texas A&M (-31.5)
Jimbo Fisher’s Texas A&M Aggies (1-1) fell apart defensively a week ago, surrendering 8.4 yards per play in a 48-33 loss to the Miami Hurricanes. This is a get-right spot at home against the UL Monroe Warhawks (2-0).
T6. Florida State (-28.5) at Boston College
One of just two conference games on this slate sees the Florida State Seminoles (2-0) as hefty road favorites over a Boston College Eagles (1-1) that limped past the Holy Cross Crusaders 31-28 in Week 2. This is another chance for Jordan Travis to pad his stats in his quest for the 2023 Heisman Trophy.
T6. Wyoming at Texas (-28.5)
Week 2’s biggest winners are favored to win by over four touchdowns at home. Steve Sarkisian and company can’t get too comfortable as the Wyoming Cowboys (2-0) already have one win over a Big 12 team on the resume after Week 1’s upset over the Texas Tech Red Raiders.
T6. Kansas (-28.5) at Nevada
The Nevada Wolf Pack (0-2) may be the worst team in the country. They lost 33-6 to an FCS team in Week 2 and surrendered a ghastly 12.4 yards per play in Week 1. They’re expected to get walloped by Lance Leipold’s Kansas Jayhawks (2-0), who are averaging 530 total yards per game.
9. Western Kentucky at Ohio State (-27.5)
It hasn’t been pretty in the early going for the Ohio State Buckeyes (2-0), but the defense looks legit, having surrendered just ten total points through two games. The offense will look to continue to improve as Kyle McCord gets more comfortable leading a stacked offense that has underperformed thus far.
T10. South Carolina at Georgia (-26.5)
The second conference game sees Shane Beamer’s South Carolina Gamecocks (1-1) as hefty underdogs against the defending national champs. The Georgia Bulldogs (2-0) have not been remotely tested this season. Still, they are expected to answer the bell with a dominant win over a reeling opponent that was manhandled in the trenches for the North Carolina Tar Heels in Week 1.
T10. Western Michigan at Iowa (-26.5)
Covering this spread will require the Iowa Hawkeyes to score at least 27 points — something they’ve done just once in their last 11 games. Kirk Ferentz’s squad will have every opportunity to do that against a Western Michigan Broncos (1-1) team that just got demolished 48-7 at the hands of the Syracuse Orange in Week 2.
T10. Oklahoma (-26.5) at Tulsa
The Oklahoma Sooners (2-0) but a 73-0 beatdown on the Arkansas State Red Wolves in Week 1, and this spread indicates that another lopsided affair could be for Brent Venables’s team after a muted 28-11 victory in Week 2. It’s a rebuilding year for Kevin Wilson in Year 1, and his squad is not expected to be competitive at home.
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