Chargers Go Off-Script, Select RB Omarion Hampton 22nd Overall

The Los Angeles Chargers have doubled down on their physical identity under head coach Jim Harbaugh, selecting North Carolina running back Omarion Hampton with the No. 22 pick in the 2025 NFL Draft. Built in the image of Harbaugh and offensive coordinator Greg Roman, the Chargers are fully committed to a ground-and-pound philosophy.

2025 NFL Mock Draft 14.0: Predicting the First 2 Rounds

Hampton, a 220-pound bruiser with excellent vision and cutback ability, becomes the second running back drafted in the first round—following Ashton Jeanty at No. 6 to Las Vegas. While not as flashy as Jeanty or TreVeyon Henderson, Hampton is highly effective when given a seam and can break away for chunk yardage. He thrives in yards after contact and fits perfectly into Roman’s run-heavy scheme.

Tackle the Odds with SportsGrid’s Expert NFL Game Picks and NFL Player Prop Picks.

The Chargers signed veteran Najee Harris to a short-term deal earlier this offseason, but Hampton is clearly viewed as the future RB1. His ability to carry the ball 20–25 times per game makes him a valuable asset to control tempo and open up opportunities for Justin Herbert through play-action and RPO sets.

Have all the intel you need? Free actionable info is one click away! Sign up for our daily newsletter.

Built behind a strong offensive line featuring Rashawn Slater, Zion Johnson, and Joe Alt, the Chargers are creating a backfield foundation for long-term success. While some may question if LA can win by running in today’s pass-heavy AFC, Harbaugh and GM Joe Hortiz see Hampton as a cornerstone piece.

This is a strategic pick, more about 2026 and beyond than a quick fix. Omarion Hampton could thrive in LA’s system—if given the full workload.

Stay ahead of the game and elevate your sports betting experience with SportsGrid.