NFL DFS: Ranking the Must-Play Defense Matchups for Week 4

Grant White
Host · Writer
1. Pittsburgh Steelers
FanDuel Salary: $4,500
Opponent: Indianapolis Colts
FanDuel Opponent Rank vs. Position: 17th
The Pittsburgh Steelers aren't getting the respect they deserve heading into Week 4's clash versus the Indianapolis Colts. Pittsburgh has stymied opponents to the tune of 229.7 yards and 8.7 points per game. That's in addition to forcing 1.7 takeaways and 3.0 sacks. Anthony Richardson has already thrown six picks this season, albeit behind a sturdy offensive line that has allowed just four sacks. Still, the T.J. Watt-led Steelers will outperform their modest salary on Sunday's main slate.
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5. Houston Texans
FanDuel Salary: $4,100
Opponent: Jacksonville Jaguars
FanDuel Opponent Rank vs. Position: 27th
The Houston Texans' offense gets the lion's share of the adulation, but it's time to start paying attention to their defensive prowess. Houston's secondary has forced interceptions in two of their first three games and is due for a bounce-back performance after last week's unbecoming result. Back at NRG Stadium, they should make life difficult on a Jacksonville Jaguars' offense that has shown no cohesion early in 2024. The Texans are due for more interceptions and fantasy points on the main slate.
Tackle the Odds with SportsGrid’s Expert NFL Game Picks and NFL Player Prop Picks.
4. New York Jets
FanDuel Salary: $4,800
Opponent: Denver Broncos
FanDuel Opponent Rank vs. Position: 24th
The Denver Broncos face a daunting cross-country trek as they head to the Meadowlands for an AFC battle with the New York Jets. That should allow the hosts to take advantage of the road-weary Broncos in an earlier-than-usual time slot. Led by Quinnen Williams, the Jets' defensive front has recaptured their glory, totaling 11 sacks over the past two weeks. They should force rookie Bo Nix into more mistakes through the air, heightening their fantasy ceiling in Week 4.
3. Los Angeles Chargers
FanDuel Salary: $3,200
Opponent: Kansas City Chiefs
FanDuel Opponent Rank vs. Position: 11th
Not surprisingly, Jim Harbaugh's tenure as head coach of the Los Angeles Chargers is off to a stout beginning. LA has held all three of their opponents to 346 yards or fewer, with only the Pittsburgh Steelers exceeding 10 points. Now, the Chargers get to settle into the comforts of home, welcoming a Kansas City Chiefs side to town. The two-time defending Super Bowl Champions haven't looked as imposing to start the season, and could easily be sitting winless instead of 3-0. We're betting the Chargers impose their defensive will en route to one of the best defensive performances of the day.
2. San Francisco 49ers
FanDuel Salary: $5,000
Opponent: New England Patriots
FanDuel Opponent Rank vs. Position: 25th
It's been an uncharacteristic start to the 2024 NFL season for the defending NFC Champion San Francisco 49ers. The Niners have allowed their last two opponents to score at least 23 points, with the Minnesota Vikings totaling over 400 yards of offense. However, Week 4's tilt versus the New England Patriots should allow the 49ers to sink back into their defensive rhythm. There's a reason why San Francisco is the priciest defense, but they are still worth the investment.
1. Pittsburgh Steelers
FanDuel Salary: $4,500
Opponent: Indianapolis Colts
FanDuel Opponent Rank vs. Position: 17th
The Pittsburgh Steelers aren't getting the respect they deserve heading into Week 4's clash versus the Indianapolis Colts. Pittsburgh has stymied opponents to the tune of 229.7 yards and 8.7 points per game. That's in addition to forcing 1.7 takeaways and 3.0 sacks. Anthony Richardson has already thrown six picks this season, albeit behind a sturdy offensive line that has allowed just four sacks. Still, the T.J. Watt-led Steelers will outperform their modest salary on Sunday's main slate.
Stay ahead of the game and elevate your sports betting experience with SportsGrid.
5. Houston Texans
FanDuel Salary: $4,100
Opponent: Jacksonville Jaguars
FanDuel Opponent Rank vs. Position: 27th
The Houston Texans' offense gets the lion's share of the adulation, but it's time to start paying attention to their defensive prowess. Houston's secondary has forced interceptions in two of their first three games and is due for a bounce-back performance after last week's unbecoming result. Back at NRG Stadium, they should make life difficult on a Jacksonville Jaguars' offense that has shown no cohesion early in 2024. The Texans are due for more interceptions and fantasy points on the main slate.
Tackle the Odds with SportsGrid’s Expert NFL Game Picks and NFL Player Prop Picks.

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