MLB Betting Guide for May 29: Padres Being Overlooked in NL?

Ben DiGiacomo
Host · Writer

We have a 16-game MLB slate stretching throughout the entire day today, so let’s dive into everything you need to know.
Kicking off the day, the future of the Pittsburgh Pirates will be on display in a doubleheader against the Detroit Tigers as Jared Jones will take the ball first against AL Cy Young hopeful Tarik Skubal, and Paul Skenes will take the mound in the second game.
Additionally, in the afternoon, the Philadelphia Phillies will look to avoid being swept by the San Francisco Giants, and the Arizona Diamondbacks and Texas Rangers will continue on with their World Series rematch after the Rangers took the first game last night. The Los Angeles Dodgers and New York Mets will close out their series today in Queens as well, so check out our +750 ultimate same-game parlay as the Dodgers aim for the sweep.
Plus, we have to shine some spotlight on the San Diego Padres as they continue to be competitive and fly under the radar. They only have a 30-28 record, but with the Braves injuries, the Padres look entirely in the mix to be the third-best team in the National League behind the Phillies and Dodgers come playoff time. Someone has to challenge the top two clubs, so why not the Padres?
Later, in the NL, Shota Imanaga will take the ball for the Chicago Cubs in their divisional battle with the Milwaukee Brewers, and the Atlanta Braves and Washington Nationals will face off once again.
Over in the American League, the Cleveland Guardians now have a narrow lead over the New York Yankees for the best record in the AL. The Guardians will face the Colorado Rockies and the Yankees will face the Los Angeles Angels tonight.
Stay with SportsGrid to be covered on everything the day will throw at us. Let’s ride!
Swing for the Fences with SportsGrid’s free daily MLB Game Picks and MLB Prop Picks.
MLB Betting Guide for May 29
Catch up on Yesterday’s Action: Rangers Take Down D-Backs | Dodgers Defeat Mets Twice | Braves’ Outlook Without Acuna
Game 1- 12:40 p.m. ET: Pittsburgh Pirates @ Detroit Tigers
- Run Line: Tigers -1.5 | Moneyline: Tigers -146 | Total: 6.5
- Where to Watch: MLB.TV | Location: Comerica Park (Detroit, MI)
- Weather Notes: Should remain clear, winds blowing out to right-center
Starting Pitching Matchup: Jared Jones (ERA: 3.05; K/9: 10.37) vs. Tarik Skubal (ERA: 2.25; K/9: 10.80)
SportsGrid’s Best Bets: Pirates ML (3-Stars, +124) | OVER 6.5 (3.5-Stars)
SportsGrid’s Predicted Game Outcome: Pirates by 0.1 Runs
SportsGrid’s Top Props: Bryan Reynolds OVER 0.5 RBIs (5-Stars, +260) | Wenceel Perez OVER 0.5 RBIs (5-Stars, +280)
1:10 p.m. ET: St. Louis Cardinals @ Cincinnati Reds
- Run Line: Reds +1.5 | Moneyline: Reds -1160 | Total: 9.5
- Where to Watch: MLB.TV | Location: Great American Ball Park (Cincinnati, OH)
- Weather Notes: Rain/storms expected in the late-afternoon, should be able to squeeze in game though.
Starting Pitching Matchup: Andre Pallante (ERA: 6.30; K/9: 5.40) vs. Frankie Montas (ERA: 4.61; K/9: 6.15)
SportsGrid’s Best Bets: Reds +1.5 (5-Stars) | Reds ML (5-Stars) | OVER 9.5 (1-Star)
SportsGrid’s Predicted Game Outcome: Reds by 1.6 Runs
SportsGrid’s Top Props: Frankie Montas UNDER 4.5 Ks (5-Stars)
2:35 p.m. ET: Arizona Diamondbacks @ Texas Rangers
- Run Line: Rangers -1.5 | Moneyline: Rangers -126 | Total: 9
- Where to Watch: MLB TV | Location: Globe Life Field (Arlington, TX)
- Weather Notes: Dome
Starting Pitching Matchup: Ryne Nelson (ERA: 6.03; K/9: 7.34) vs. Dane Dunning (ERA: 4.43; K/9: 10.40)
SportsGrid’s Best Bets: Rangers -1.5 (2.5-Stars) | Rangers ML (2-Stars) | UNDER 9 (1-Star)
SportsGrid’s Predicted Game Outcome: Rangers by 1.0 Runs
SportsGrid’s Top Props: Lourdes Gurriel Jr. OVER 0.5 RBIs (5-Stars, +155) | Dane Dunning OVER 4.5 Ks (5-Stars)
3:45 p.m. ET: Philadelphia Phillies @ San Francisco Giants
- Run Line: Phillies -1.5 | Moneyline: Phillies -132 | Total: 7.5
- Where to Watch: MLB.TV | Location: Oracle Park (San Francisco, CA)
- Weather Notes: Clear, winds blowing out to left-center
Starting Pitching Matchup: Cristopher Sanchez (ERA: 3.15; K/9: 8.12) vs. Kyle Harrison (ERA: 3.90; K/9: 8.25)
SportsGrid’s Best Bets: Phillies -1.5 (5-Stars) | Phillies ML (5-Stars) | OVER 7.5 (2.5-Stars)
SportsGrid’s Predicted Game Outcome: Phillies by 2.2 Runs
SportsGrid’s Top Props: Edmundo Sosa OVER 0.5 RBIs (5-Stars, +185) | Wilmer Flores OVER 0.5 RBIs (5-Stars, +185)
4:10 p.m. ET: Miami Marlins @ San Diego Padres
- Run Line: Padres -1.5 | Moneyline: Padres -168 | Total: 7.5
- Where to Watch: MLB.TV | Location: Petco Park (San Diego, CA)
- Weather Notes: Clear, winds blowing out to right-center
Starting Pitching Matchup: Braxton Garrett (ERA: 5.30; K/9: 9.16) vs. Yu Darvish (ERA: 3.04; K/9: 8.61)
SportsGrid’s Best Bets: Padres -1.5 (5-Stars) | Padres ML (3.5-Stars) | OVER 7.5 (4-Stars)
SportsGrid’s Predicted Game Outcome: Padres by 2.0 runs
SportsGrid’s Top Props: Josh Bell OVER 0.5 RBIs (5-Stars, +195) | Yu Darvish UNDER 5.5 Ks (5-Stars, +126)
Game 2- 4:10 p.m. ET: Pittsburgh Pirates @ Detroit Tigers
- Run Line: N/A | Moneyline: N/A | Total: N/A
- Where to Watch: MLB.TV | Location: Comerica Park (Detroit, MI)
- Weather Notes: Clear, winds blowing out to right-center
Starting Pitching Matchup: Paul Skenes (ERA: 2.25; K/9: 11.81) vs. Undecided
SportsGrid’s Best Bets: Awaiting Odds
SportsGrid’s Predicted Game Outcome: Pirates by 0.1 Runs
SportsGrid’s Top Props: Awaiting Odds
4:10 p.m. ET: Los Angeles Dodgers @ New York Mets
- Run Line: Dodgers -1.5 | Moneyline: Dodgers -132 | Total: 8.5
- Where to Watch: MLB TV | Location: Citi Field (Queens, NY)
- Weather Notes: Clear, winds blowing out to center
Starting Pitching Matchup: James Paxton (ERA: 3.49; K/9: 5.14) vs. David Peterson (Season Debut)
SportsGrid’s Best Bets: Dodgers -1.5 (1.5-Stars) | Dodgers ML (3.5-Stars) | UNDER 8.5 (2-Stars)
SportsGrid’s Predicted Game Outcome: Dodgers by 1.2 Runs
SportsGrid’s Top Props: Awaiting Props
6:35 p.m. ET: Boston Red Sox @ Baltimore Orioles
- Run Line: Orioles -1.5 | Moneyline: Orioles -178 | Total: 7.5
- Where to Watch: MLB.TV | Location: Camden Yards (Baltimore, MD)
- Weather Notes: Rain expected in early evening, should be played but a late-start is expected
Starting Pitching Matchup: Kutter Crawford (ERA: 2.89; K/9: 8.81) vs. Corbin Burnes (ERA: 2.60; K/9: 9.05)
SportsGrid’s Best Bet: Red Sox ML (2-Stars) | OVER 7.5 (5-Stars)
SportsGrid’s Predicted Game Outcome: Orioles by 0.6 Runs
SportsGrid’s Top Props: Rafael Devers OVER 0.5 RBIs (5-Stars, +140) | Adley Rutschman OVER 0.5 RBIs (5-Stars, +170)
6:50 p.m. ET: Oakland Athletics @ Tampa Bay Rays
- Run Line: Rays -1.5 | Moneyline: Rays -178 | Total: 8.5
- Where to Watch: MLB.TV | Location: Tropicana Field (St. Petersburg, FL)
- Weather Notes: Dome
Starting Pitching Matchup: Ryan Pepiot (ERA: 3.98; K/9: 9.74) vs. Joey Estes (ERA: 7.47; K/9: 8.62)
SportsGrid’s Best Bets: Rays -1.5 (3-Stars) | OVER 8.5 (1-Star)
SportsGrid’s Predicted Game Outcome: Rays by 1.7 Runs
SportsGrid’s Top Props: Ryan Pepiot UNDER 6.5 Ks (5-Stars)
7:20 p.m ET: Washington Nationals @ Atlanta Braves
- Run Line: Braves -1.5 | Moneyline: Braves -158 | Total: 8.5
- Where to Watch: MLB.TV | Location: Truist Park (Atlanta, GA)
- Weather Notes: Clear, winds blowing out to left-center
Starting Pitching Matchup: MacKenzie Gore (ERA: 3.04; K/9: 10.46) vs. Spencer Schwellenbach (MLB Debut)
SportsGrid’s Best Bets: N/A
SportsGrid’s Predicted Game Outcome: N/A
SportsGrid’s Top Props: Awaiting Props
7:40 p.m. ET: Chicago Cubs @ Milwaukee Brewers
- Run Line: Brewers -1.5 | Moneyline: Brewers -136 | Total: 7.5
- Where to Watch: MLB TV | Location: American Family Field (Milwaukee, WI)
- Weather Notes: Dome
Starting Pitching Matchup: Shota Imanaga (ERA: 0.84; K/9: 9.73) vs. Bryse Wilson (ERA: 2.86; K/9: 7.77)
SportsGrid’s Best Bet: OVER 7.5 (1-Star)
SportsGrid’s Predicted Game Outcome: Cubs by 0.8 Runs
SportsGrid’s Top Props: Christopher Morel OVER 0.5 RBIs (5-Stars, +130) | Bryse Wilson UNDER 5.5 Ks (5-Stars)
7:40 p.m. ET: Kansas City Royals @ Minnesota Twins
- Run Line: Twins -1.5 | Moneyline: Twins -130 | Total: 7.5
- Where to Watch: MLB.TV | Location: Target Field (Minneapolis, MN)
- Weather Notes: Clear, winds blowing in from right
Starting Pitching Matchup: Seth Lugo (ERA: 1.74; K/9: 7.59) vs. Bailey Ober (ERA: 4.33; K/9: 9.35)
SportsGrid’s Best Bet: UNDER 7.5 (1-Star)
SportsGrid’s Predicted Game Outcome: Twins by 0.2 Runs
SportsGrid’s Top Props: Bobby Witt Jr. OVER 0.5 RBIs (5-Stars, +135) | Ryan Jeffers OVER 0.5 RBIs (5-Stars, +160)
7:40 p.m. ET: Toronto Blue Jays @ Chicago White Sox
- Run Line: Blue Jays -1.5 | Moneyline: Blue Jays -184 | Total: 8.5
- Where to Watch: MLB.TV | Location: Guaranteed Rate Field (Chicago, IL)
- Weather Notes: Clear, winds blowing out to right
Starting Pitching Matchup: Alek Manoah (ERA: 3.97; K/9: 9.13) vs. Chris Flexen (ERA: 5.69; K/9: 6.61)
SportsGrid’s Best Bets: OVER 8.5 (2-Stars)
SportsGrid’s Predicted Game Outcome: Blue Jays by 1.3 Runs
SportsGrid’s Top Props: Alek Manoah UNDER 5.5 Ks (5-Stars) | Andrew Benintendi OVER 0.5 RBIs (5-Stars, +210)
8:40 p.m ET: Cleveland Guardians @ Colorado Rockies
- Run Line: Guardians -1.5 | Moneyline: Guardians -156 | Total: 10.5
- Where to Watch: MLB.TV | Location: Coors Field (Denver, CO)
- Weather Notes: Clear, winds blowing out to left
Starting Pitching Matchup: Logan Allen (ERA: 4.90; K/9: 7.89) vs. Ty Blach (ERA: 4.55; K/9: 3.90)
SportsGrid’s Best Bet: OVER 10.5 (3-Stars)
SportsGrid’s Predicted Game Outcome: Guardians by 1.4 Runs
SportsGrid’s Top Props: Logan Allen UNDER 4.5 Ks (4-Stars, +118) | Hunter Goodman OVER 0.5 RBIs (5-Stars, +155)
9:38 p.m. ET: New York Yankees @ Los Angeles Angels
- Run Line: Yankees -1.5 | Moneyline: Yankees -188 | Total: 8.5
- Where to Watch: MLB.TV | Location: Angel Stadium (Anaheim, CA)
- Weather Notes: Clear, winds blowing out to left-center
Starting Pitching Matchup: Luis Gil (ERA: 2.11; K/9: 11.39) vs. Tyler Anderson (ERA: 2.52; K/9: 6.16)
SportsGrid’s Best Bets: Angels +1.5 (-Stars) | Angels ML (5-Stars, +158) | OVER 8.5 (1-Star)
SportsGrid’s Predicted Game Outcome: Angels by 0.5 Runs
SportsGrid’s Top Props: Luis Gil OVER 6.5 Ks (5-Stars)
9:40 p.m. ET: Houston Astros @ Seattle Mariners
- Run Line: Astros -1.5 | Moneyline: Astros -102 | Total: 7
- Where to Watch: MLB.TV | Location: T-Mobile Park (Seattle, WA)
- Weather Notes: Dome
Starting Pitching Matchup: Justin Verlander (ERA: 3.60; K/9: 7.88) vs. George Kirby (ERA: 4.33; K/9: 8.23)
SportsGrid’s Best Bets: Astros -1.5 (1.5-Stars) | Astros ML (3.5-Stars) | OVER 7 (3.5-Stars)
SportsGrid’s Predicted Game Outcome: Astros by 0.6 Runs
SportsGrid’s Top Props: Justin Verlander UNDER 6.5 Ks (5-Stars) | Luke Raley OVER 0.5 Hits (5-Stars, -125)
