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Top 3 First-Round Running Backs in Fantasy Football

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The undisputed #1 overall fantasy pick in 2025. Chase is matchup-proof, target-dominant, and has WR1 upside every single week.
Tackle the Odds with SportsGrid’s Expert <a href="https://www.sportsgrid.com/nfl/picks">NFL Game Picks</a> and <a href="https://www.sportsgrid.com/nfl/player-props">NFL Player Prop Picks</a>.

1. Ja’Marr Chase – Cincinnati Bengals

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A target machine in the slot, Amon-Ra is one of the safest high-end WR picks you can make. In full PPR, he's nearly unmatchable.

2. Amon-Ra St. Brown – Detroit Lions

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Don't be scared of the QB situation — Nabers’ talent is elite. If he gets enough volume, he can leap into the top 3 WRs.

3. Malik Nabers – New York Giants

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Nico became <a href="https://www.sportsgrid.com/nfl/players/cj-stroud/1905">C.J. Stroud</a>’s go-to guy last year. He’ll continue to dominate targets and red zone looks. A value at his current ADP.

NFL: AFC Wild Card Round-Los Angeles Chargers at Houston Texans

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Emerging as the WR1 in Jacksonville, Thomas is the kind of WR3 who can play like a WR1 some weeks.
March down the field with SportsGrid’s FREE Top <a href="https://www.sportsgrid.com/nfl/picks">NFL Game Picks</a> and <a href="https://www.sportsgrid.com/nfl/player-props">NFL Player Prop Picks</a> weekly!

5. Brian Thomas Jr. – Jacksonville Jaguars

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If Atlanta’s offense clicks, London is a prime breakout candidate. Huge frame, great hands, and finally some QB consistency.

6. Drake London – Atlanta Falcons

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One of last year’s biggest surprises. Nacua brings great PPR upside and has established chemistry with <a href="https://www.sportsgrid.com/nfl/players/matthew-stafford/1251">Matthew Stafford</a>.

7. Puka Nacua – Los Angeles Rams

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JSN is ready to take over as Seattle’s top WR. He’ll be a PPR goldmine if <a href="https://www.sportsgrid.com/nfl/players/sam-darnold/2614">Sam Darnold</a> keeps him in rhythm.

8. Jaxon Smith-Njigba – Seattle Seahawks

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Still dangerous, but age and injury risk push him down. Great value in best ball or as a WR2 in redraft.
Stay ahead of the game and elevate your sports betting experience with<a href="https://www.sportsgrid.com/"> SportsGrid</a>.

9. Tyreek Hill – Miami Dolphins

NFL Fantasy Football 2025: Top Wide Receiver Rankings

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There is no shortage of elite wide receivers in fantasy football. Check out our rankings, including breakdowns of the top nine wide receivers into tiers.

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