NFL · 20 minutes ago

Ranking The Top 10 Potential Upsets For NFL Week 6

Patrick Kelleher

Host · Writer

10. New Orleans Saints @ New York Giants
The Giants host the Saints at MetLife Stadium this Sunday. As hard as it might be to believe, the away team, with a 1-4 record, is the favorite against the home team, with a 3-1-1 record. This may not be an "upset" in the eyes of many, but the Giants have the chance to take even further command of the NFC East.
1. Los Angeles Chargers @ Kansas City Chiefs
This is a surprise that would completely shock the NFL world. The Chargers have been the biggest disappointment of 2026 thus far, as they still search for their first victory. The Chiefs look to be back in their old form and are the heavy favorites to take back the AFC West crown. The phrase "any given Sunday" has never been more prevalent than this divisional matchup this week. Can LA finally get it done and shock the world?
2. Baltimore Ravens @ Cleveland Browns
Despite all their faults over the years, the Cleveland Browns have always made life tough for their divisional opponents. Like Buffalo, the Ravens are coming off an overtime thriller this past Sunday night, defeating the Falcons on a Tyler Loop game-winning field goal. The dawg-pound has never been an easy place to play, especially for division rivals. Coming off a tough loss to the Jets, Cleveland looks like a bounce-back team.
3. Buffalo Bills @ Las Vegas Raiders
The Bills are coming off the game of the year so far in the NFL, defeating the LA Rams in an overtime thriller on Monday Night. Conversely, the Raiders are coming off their worst performance of the season against the New England Patriots. This feels like a classic letdown spot on the road against a team that is desperate for a bounce-back.
4. Tennessee Titans @ Indianapolis Colts
The Tennessee Titans are now one of just two teams left without a victory as we approach Week 6. They look completely lost on both sides of the ball, and fans have no reason to believe that will change on the road this week. At the end of the day, it's a divisional matchup, and the Titans have to find the win column eventually. The Colts look vulnerable on both sides of the ball, making this Tennessee's best opportunity thus far to earn their first win.
5. Pittsburgh Steelers @ Tampa Bay Buccaneers
The Tampa Bay Buccaneers found the win column for the first time in 2026 last Thursday night, picking up a 24-16 road victory over the Dallas Cowboys. They now host the Steelers this week, with rookie QB Jalon Daniels getting more comfortable in the offense. Pittsburgh has been notoriously up and down over the last few years. Coming off a victory last week, this feels like a letdown spot on the road in Tampa.
6. Houston Texans @ Jacksonville Jaguars (London)
The Houston Texans finally found the win column last week, taking care of business against the lowly Titans. They now find themselves across the pond against another division rival, the Jacksonville Jaguars. Divisional games are always a toss-up to begin with, and now Houston is riding some momentum after finding something on offense last week and welcoming Marvin Harrison Jr. to the lineup.
7. Chicago Bears @ Atlanta Falcons
This week should see the return of Caleb Williams for the Chicago Bears as they travel to Atlanta to take on the Falcons. After a brutal 0-2 start, the Falcons have looked like a completely different team since Michael Penix Jr. returned to the lineup. Caleb will most likely have some rust to knock off, making this a prime opportunity for a Falcons upset.
8. New York Jets @ New England Patriots
The history of this rivalry over the past 15 years has been completely dominated by the New England Patriots. The last time these two teams met, the Patriots won handily by 32. The Jets have proven to be more competitive this season. Coming off a win last week against Cleveland, this would easily be the most significant win of Aaron Glenn's tenure if he can pull it off.
9. Carolina Panthers @ Philadelphia Eagles
Going into the season, the Carolina Panthers beating the Philadelphia Eagles at Lincoln Financial Field would be considered one of the season's biggest surprises. However, with Philadelphia in full-on crisis mode, the shock value of a Panthers upset has somewhat diminished.
10. New Orleans Saints @ New York Giants
The Giants host the Saints at MetLife Stadium this Sunday. As hard as it might be to believe, the away team, with a 1-4 record, is the favorite against the home team, with a 3-1-1 record. This may not be an "upset" in the eyes of many, but the Giants have the chance to take even further command of the NFC East.
1. Los Angeles Chargers @ Kansas City Chiefs
This is a surprise that would completely shock the NFL world. The Chargers have been the biggest disappointment of 2026 thus far, as they still search for their first victory. The Chiefs look to be back in their old form and are the heavy favorites to take back the AFC West crown. The phrase "any given Sunday" has never been more prevalent than this divisional matchup this week. Can LA finally get it done and shock the world?

Ranking The Top 10 Potential Upsets For NFL Week 6

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