MLB Betting Guide for Opening Day 2024: Baseball is Back!

Alas, baseball is back! 2024 MLB Opening Day has finally arrived, and we have you covered with everything you need to know as MLB action begins today.

Kicking off the day, Corbin Burnes debuts with the Baltimore Orioles against the Los Angeles Angels, who are moving on without Shohei Ohtani. Ohtani’s Dodgers are back in action after splitting their Seoul Series with the San Diego Padres as they welcome the St. Louis Cardinals to Dodger Stadium.

The Houston Astros and New York Yankees face off in a potential ALCS preview, giving us one of the league’s best present-day rivalries right from the jump. Will the Yankees’ new additions be enough to propel them back into contention?

Headling the late window, the Texas Rangers will celebrate their World Series victory as the improved Chicago Cubs look to spoil the party. Does Texas have what it takes to repeat, or will the injuries to their pitching staff at the start of the season be too much to overcome?

It will be a great baseball day, so stay with SportsGrid all day to have you covered on everything the day will throw at us. Let’s ride!

Swing for the Fences with SportsGrid’s free daily MLB Game Picks and MLB Prop Picks.

MLB Betting Guide for March 28

3:05 p.m. ET: Los Angeles Angels @ Baltimore Orioles

Run Line: Orioles -1.5 | Moneyline: Orioles -172 | Total: 7.5
Where to Watch: MLB.TV | Location: Oriole Park at Camden Yards (Baltimore, MD)
Weather Notes: Likelihood of playing through light rain, winds blowing in

Starting Pitching Matchup: Patrick Sandoval vs. Corbin Burnes

SportsGrid’s Best Bet: OVER 7.5 Runs (5-Stars)

SportsGrid’s Predicted Game Outcome: Orioles by 1 Run

SportsGrid’s Top Props: Logan O’Hoppe OVER 0.5 RBIs (5-Stars, +230) | Gunnar Henderson OVER 0.5 RBIs (5-Stars, +140)

4:10 p.m. ET: St. Louis Cardinals @ Los Angeles Dodgers

Run Line: Dodgers -1.5 | Moneyline: Dodgers -230 | Total: 8.5
Where to Watch: MLB.TV | Location: Dodger Stadium (Los Angeles, CA)
Weather Notes: Clear, sunny, winds blowing out to center

Starting Pitching Matchup: Miles Mikolas vs. Tyler Glasnow (ERA: 3.60; K/9: 5.40)

SportsGrid’s Best Bet: UNDER 8.5 Runs (1-Star)

SportsGrid’s Predicted Game Outcome: Dodgers by 2 Runs

SportsGrid’s Top Props: Nolan Gorman OVER 0.5 RBIs (5-Stars, +185) | Mookie Betts OVER 0.5 RBIs (3.5-Stars, +120)

More Cardinals-Dodgers: Ohtani Probe

4:10 p.m. ET: Pittsburgh Pirates @ Miami Marlins

Run Line: Marlins -1.5 | Moneyline: Marlins -134 | Total: 7.5
Where to Watch: MLB.TV | Location: LoanDepot Park (Miami, FL)
Weather Notes: Dome

Starting Pitching Matchup: Mitch Keller vs. Jesus Luzardo

SportsGrid’s Best Bets: Marlins ML (2-Stars) | UNDER 7.5 Runs (2-Star)

SportsGrid’s Predicted Game Outcome: Marlins by 1 Run

SportsGrid’s Top Props: Ke’Bryan Hayes OVER 0.5 RBIs (5-Stars, +175) | Bryan De La Cruz OVER 0.5 RBIs (3.5-Stars, +210)

4:10 p.m. ET: Toronto Blue Jays @ Tampa Bay Rays

Run Line: Rays -1.5 | Moneyline: Rays -136 | Total: 7.5
Where to Watch: MLB.TV | Location: Tropicana Field (St. Petersburg, FL)
Weather Notes: Dome

Starting Pitching Matchup: Jose Berrios vs. Zach Eflin

SportsGrid’s Best Bets: Rays ML (5-Stars) | OVER 7.5 Runs (2.5-Stars)

SportsGrid’s Predicted Game Outcome: Rays by 2 Runs

SportsGrid’s Top Props: George Springer OVER 0.5 RBIs (5-Stars, +210) | Zach Eflin OVER 4.5 Ks (5-Stars)

4:10 p.m. ET: Washington Nationals @ Cincinnati Reds

Run Line: Reds -1.5 | Moneyline: Reds -152 | Total: 9
Where to Watch: MLB.TV | Location: Great American Ball Park (Cincinnati, OH)
Weather Notes: Clear, sunny, winds blowing out to left

Starting Pitching Matchup: Josiah Gray vs. Frankie Montas

SportsGrid’s Best Bets: Reds ML (3.5-Stars) | OVER 9 Runs (4-Stars)

SportsGrid’s Predicted Game Outcome: Reds by 2 Runs

SportsGrid’s Top Props: Lane Thomas OVER 0.5 RBIs (5-Stars, +155) | Frankie Montas UNDER 4.5 Ks (5-Stars)

4:10 p.m. ET: Minnesota Twins @ Kansas City Royals

Run Line: Twins -1.5 | Moneyline: Twins -132 | Total: 8.5
Where to Watch: MLB.TV | Location: Kauffman Stadium (Kansas City, MO)
Weather Notes: Clear, sunny, winds blowing out to left-center

Starting Pitching Matchup: Pablo Lopez vs. Cole Ragans

SportsGrid’s Best Bet: OVER 8.5 Runs (3.5-Stars)

SportsGrid’s Predicted Game Outcome: Twins by 1 Run

SportsGrid’s Top Props: Pablo Lopez OVER 5.5 Ks (5-Stars) | Cole Ragans UNDER 5.5 Ks (5-Stars)

4:10 p.m. ET: Detroit Tigers @ Chicago White Sox

Run Line: Tigers -1.5 | Moneyline: Tigers -172 | Total: 7.5
Where to Watch: MLB.TV | Location: Guaranteed Rate Field (Chicago, IL)
Weather Notes: Clear, sunny, below-50, winds blowing out to left,

Starting Pitching Matchup: Tarik Skubal vs. Garrett Crochet

SportsGrid’s Best Bets: White Sox ML (5-Stars, +144) | OVER 7.5 Runs (5-Stars)

SportsGrid’s Predicted Game Outcome: White Sox by 2 Runs

SportsGrid’s Top Props: Spencer Torkelson OVER 0.5 RBIs (5-Stars) | Garrett Crochet UNDER 4.5 Ks (5-Stars)

4:10 p.m. ET: New York Yankees @ Houston Astros

Run Line: Astros -1.5 | Moneyline: Astros -152 | Total: 8.5
Where to Watch: MLB.TV | Location: Minute Maid Park (Houston, TX)
Weather Notes: Clear, sunny, open roof

Starting Pitching Matchup: Nestor Cortes vs. Framber Valdez

SportsGrid’s Best Bets: Astros ML (3.5-Stars) | UNDER 8.5 (1-Star)

SportsGrid’s Predicted Game Outcome: Astros by 2 Runs

SportsGrid’s Top Props: Aaron Judge OVER 0.5 RBIs (5-Stars, +125) | Yordan Alvarez OVER 0.5 RBIs (5-Stars, +135)

4:10 p.m. ET: San Francisco Giants @ San Diego Padres

Run Line: Giants -1.5 | Moneyline: Giants -108 | Total: 7.5
Where to Watch: MLB.TV | Location: Petco Park (San Diego, CA)
Weather Notes: Clear, sunny, winds blowing in

Starting Pitching Matchup: Logan Webb vs. Yu Darvish (ERA: 0.00; K/9: 7.36)

SportsGrid’s Best Bets: Padres ML (4-Stars) | OVER 7.5 (1-Star)

SportsGrid’s Predicted Game Outcome: Padres by 2 Runs

SportsGrid’s Top Props: Manny Machado OVER 0.5 RBIs (5-Stars, +145) | Logan Webb OVER 4.5 Ks (4.5-Stars)

7:35 p.m. ET: Chicago Cubs @ Texas Rangers

Run Line: Rangers -1.5 | Moneyline: Rangers -118 | Total: 8.5
Where to Watch: ESPN | Location: Globe Life Field (Arlington, TX)
Weather Notes: Dome

Starting Pitching Matchup: Justin Steele vs. Nathan Eovaldi

Sports Grid’s Best Bet: UNDER 8.5 Runs (2.5-Stars)

SportsGrid’s Predicted Game Outcome: Rangers by 2 Runs

SportsGrid’s Top Props: Justin Steele OVER 4.5 Ks (5-Stars) | Adolis Garcia OVER 0.5 HRs (5-Stars, +400)

10:07 p.m. ET: Cleveland Guardians @ Oakland Athletics

Run Line: Guardians -1.5 | Moneyline: Guardians -154 | Total: 7.5
Where to Watch: MLB.TV | Location: Oakland Coliseum (Oakland, CA)
Weather Notes: Clear, sunny, winds blowing out to center

Starting Pitching Matchup: Shane Bieber vs. Alex Wood

SportsGrid’s Best Bets: Atheltics ML (1.5-Stars, +130) | UNDER 7.5 (1-Star)

SportsGrid’s Predicted Game Outcome: Guardians by 1 Run

SportsGrid’s Top Props: Shane Bieber UNDER 6.5 Ks (5-Stars) | Seth Brown OVER 0.5 RBIs (5-Stars, +185)

10:10 p.m. ET: Boston Red Sox @ Seattle Mariners

Run Line: Mariners -1.5 | Moneyline: Mariners -168 | Total: 7.5
Where to Watch: MLB.TV | Location: T-Mobile Park (Seattle, WA)
Weather Notes: Dome

Starting Pitching Matchup: Brayan Bello vs. Luis Castillo

SportsGrid’s Best Bet: OVER 7.5 (2-Stars)

SportsGrid’s Predicted Game Outcome: Mariners by 2 Runs

SportsGrid’s Top Props: Triston Casas OVER 0.5 RBIs (5-Stars, +200) | Mitch Garver OVER 0.5 RBIs (5-Stars, +150)

10:07 p.m. ET: Colorado Rockies @ Arizona Diamondbacks

Run Line: Diamondbacks -1.5 | Moneyline: Diamondbacks -230 | Total: 8.5
Where to Watch: MLB.TV | Location: Chase Field (Phoenix, AZ)
Weather Notes: Dome

Starting Pitching Matchup: Kyle Freeland vs. Zac Gallen

SportsGrid’s Best Bets: Rockies ML (5-Stars, +184) | OVER 8.5 (2.5-Stars)

SportsGrid’s Predicted Game Outcome: Diamondbacks by 1 Run

SportsGrid’s Top Props: Nolan Jones OVER 0.5 RBIs (5-Stars, +210) | Zac Gallen UNDER 6.5 Ks (5-Stars)

More Rockies-Diamondbacks: Jordan Montgomery’s Deal with Arizona