2. Patrick Mahomes
Throughout his career, Patrick Mahomes has earned a reputation as one of the most elusive quarterbacks in the league. While that doesn't always translate to scoring opportunities, we expect him to create rushing lanes on Friday.
Mahomes is a steady force when it comes to rushing the ball. The two-time MVP has at least 58 rushing attempts and 307 rushing yards over his previous five seasons. Across that stretch, he's totaled ten touchdowns, while recording multiple scores in all but one of those campaigns.
Moreover, Mahomes has victimized the Chargers more than any other team. In 12 career starts versus the Chargers, the Chiefs' field general has accumulated 315 rushing yards on 51 carries, both career-highs versus a particular opponent.
Curiously, Mahomes has not found the endzone against this division rival. Still, we see immense value in backing him to buck that unflattering trend in Week 1.
Patrick Mahomes Any Time Touchdown Scorer: +460