Predicting Every NFL Week 10 Game With Score Projections

Grant White
Host · Writer
The NFL Trade Deadline is behind us, and we are heading into Week 10. The playoff races only intensify from here as we head into the stretch drive of the season.
Check out our weekly predictions for every Week 10 NFL contest!
Las Vegas Raiders vs Denver Broncos
- Stadium: Empower Field at Mile High
- Location: Denver, CO
- Time: Thursday 8:15 p.m. ET
- Spread: DEN -9.5 | Total: 42.5
- Moneyline: DEN -700 | LV +450
The Broncos have railroaded the competition recently, winning six straight. The Raiders don’t stand a chance at Mile High.
Predicted Outcome: Broncos 35 – Raiders 13
Atlanta Falcons vs Indianapolis Colts
- Stadium: Olympic Stadium Berlin
- Location: Berlin, DE
- Time: Sunday 9:30 p.m. ET
- Spread: IND -6.5 | Total: 48.5
- Moneyline: IND -340 | ATL +270
The Falcons consistently get in their own way. A late-game blunder will cost them the game against the Colts.
Predicted Outcome: Colts 24 – Falcons 21
Baltimore Ravens vs Minnesota Vikings
- Stadium: U.S. Bank Stadium
- Location: Minneapolis, MN
- Time: Sunday 1:00 p.m. ET
- Spread: BAL -4.5 | Total: 48.5
- Moneyline: BAL -230 | MIN +195
Asking the Ravens to cover this number on the road is a big ask. Still, this is a classic letdown spot for the Vikings.
Predicted Outcome: Ravens 28 – Vikings 24
New England Patriots vs Tampa Bay Buccaneers
- Stadium: Raymond James Stadium
- Location: Tampa, FL
- Time: Sunday 1:00 p.m. ET
- Spread: TB -2.5 | Total: 48.5
- Moneyline: TB -145 | NE +125
While everyone is fawning over other AFC powerhouses, the Patriots have re-established themselves as a force. An upset win over the Bucs still won’t be enough, though.
Predicted Outcome: Patriots 31 – Buccaneers 23
Jacksonville Jaguars vs Houston Texans
- Stadium: NRG Stadium
- Location: Houston, TX
- Time: Sunday 1:00 p.m. ET
- Spread: JAX -1.5 | Total: 37.5
- Moneyline: JAX -125 | HOU +105
The Texans may be allergic to offense, but no way they deserve to be home underdogs versus the Jags.
Predicted Outcome: Texans 14 – Jaguars 12
Cleveland Browns vs New York Jets
- Stadium: MetLife Stadium
- Location: East Rutherford, NJ
- Time: Sunday 1:00 p.m. ET
- Spread: CLE -2.5 | Total: 38.5
- Moneyline: CLE -135 | NYJ +115
The Jets will be fielding a CFL-caliber team. It sounds crazy, but the Browns deserve more love.
Predicted Outcome: Browns 17 – Jets 10
New Orleans Saints vs Carolina Panthers
- Stadium: Bank of America Stadium
- Location: Charlotte, NC
- Time: Sunday 1:00 p.m. ET
- Spread: CAR -5.5 | Total: 39.5
- Moneyline: CAR -240 | NO +200
The Panthers have a path to the postseason. The Saints are marching straight to the NFL Draft podium.
Predicted Outcome: Panthers 31 – Saints 14
New York Giants vs Chicago Bears
- Stadium: Soldier Stadium
- Location: Chicago, IL
- Time: Sunday 1:00 p.m. ET
- Spread: CHI -4.5 | Total: 46.5
- Moneyline: CHI -215 | NYG +180
We are no longer shocked by how the Giants decide to lose games. The Bears carry their momentum into Week 11.
Predicted Outcome: Bears 18 – Giants 10
Buffalo Bills vs Miami Dolphins
- Stadium: Hard Rock Stadium
- Location: Miami, FL
- Time: Sunday 1:00 p.m. ET
- Spread: BUF -8.5 | Total: 50.5
- Moneyline: BUF -600 | MIA +400
How Mike McDaniel still has a job is beyond comprehension. The Bills trounce Miami at home.
Predicted Outcome: Bills 42 – Dolphins 17
Arizona Cardinals vs Seattle Seahawks
- Stadium: Lumen Stadium
- Location: Seattle, WA
- Time: Sunday 4:05 p.m. ET
- Spread: SEA -6.5 | Total: 45.5
- Moneyline: SEA -300 | ARI +250
The Cardinals are getting way too much credit for their win on MNF. They will look unrecognizable versus the Seahawks.
Predicted Outcome: Seahawks 40 | Cardinals 23
Los Angeles Rams vs San Francisco 49ers
- Stadium: Levi’s Stadium
- Location: Santa Clara, CA
- Time: Sunday 4:25 p.m. ET
- Spread: LAR -4.5 | Total: 49.5
- Moneyline: LAR -215 | SF +180
The Rams may be the better team, but no way they cover this spread at Levi’s Stadium. Count us as believers in the 49ers this weekend.
Predicted Outcome: 49ers 21 – Rams 20
Detroit Lions vs Washington Commanders
- Stadium: Northwest Stadium
- Location: Landover, MD
- Time: Sunday 4:25 p.m. ET
- Spread: DET -8.5 | Total: 49.5
- Moneyline: DET -450 | WSH +340
This will be the highest-scoring game of the week, but the Commanders won’t be able to keep pace with the Lions.
Predicted Outcome: Lions 42 – Commanders 35
Pittsburgh Steelers vs Los Angeles Chargers
- Stadium: SoFi Stadium
- Location: Inglewood, CA
- Time: Sunday 8:20 p.m. ET
- Spread: LAC -2.5 | Total: 44.5
- Moneyline: LAC -145 | PIT +125
We no longer trust the Steelers’ defense. Expect the Chargers to impose their offense on SNF.
Predicted Outcome: Chargers 24 – Steelers 17
Philadelphia Eagles vs Green Bay Packers
- Stadium: Lambeau Field
- Location: Green Bay, WI
- Time: Monday 8:15 p.m. ET
- Spread: GB -2.5 | Total: 46.5
- Moneyline: GB -130 | PHI +110
The Packers have turned heads this season, but the Eagles offer a reality check on primetime.
Predicted Outcome: Eagles 27 – Packers 24
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