Predicting Every NFL Week 6 Game With Score Projections

The NFL action only intensifies with each passing week, and Week 6 is shaping up to be a doozy. Check out our side, spread, and total predictions for every matchup this week!

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Philadelphia Eagles vs. New York Giants

• Stadium: MetLife Stadium
• Location: East Rutherford, NJ
• Time: Thursday 8:15 p.m. ET
• Spread: PHI -7.5 | Total: 40.5
• Moneyline: PHI -450| NYG +340

The Eagles should be playing with a chip on their shoulder in this one-sided NFC East clash.

Predicted Outcome: Eagles 24 – Giants 10

Denver Broncos vs. New York Jets

• Stadium: Tottenham Hotspur Stadium
• Location: London, England
• Time: Sunday 9:30 a.m. ET
• Spread: DEN -6.5 | Total: 43.5
• Moneyline: DEN -380 | NYJ +290

Expect a tight defensive battle as the Jets and Broncos get to know each other in London. Jets cover, but Denver wins.

Predicted Outcome: Broncos 16 – Jets 10

Arizona Cardinals vs. Indianapolis Colts

• Stadium: Lucas Oil Stadium
• Location: Indianapolis, IN
• Time: Sunday 1:00 p.m. ET
• Spread: IND -7.5 | Total: 46.5
• Moneyline: IND -360 | ARI +280

The Cardinals’ offense has sputtered this season, and the Colts’ defense will be up to the task.

Predicted Outcome: Colts 28 – Cardinals 18

Los Angeles Rams vs. Baltimore Ravens

• Stadium: M&T Bank Stadium
• Location: Baltimore, MD
• Time: Sunday 1:00 p.m. ET
• Spread: LAR -7.5 | Total: 45.5
• Moneyline: LAR -400 | BAL +300

The Ravens’ offense or defense won’t have an answer for the Rams. 

Predicted Outcome: Rams 24 – Ravens 14 

Cleveland Browns vs. Pittsburgh Steelers

• Stadium: Acrisure Stadium
• Location: Pittsburgh, PA
• Time: Sunday 1:00 p.m. ET
• Spread: PIT -6.5 | Total: 38.5
• Moneyline: PIT -280 | CLE +230

This will be a classic AFC North battle. Steelers prevail on defense.

Predicted Outcome: Steelers 17 – Browns 14

Seattle Seahawks vs. Jacksonville Jaguars

• Stadium: EverBank Stadium
• Location: Jacksonville, FL
• Time: Sunday 1:00 p.m. ET
• Spread: SEA -1.5 | Total: 47.5
• Moneyline: SEA -110 | JAX – 110

Bettors expect this to be a flat spot for the Jags. But an early start sinks the Seahawks in this non-conference battle.

Predicted Outcome: Jaguars 31 – Seahawks 24

Los Angeles Chargers vs. Miami Dolphins

• Stadium: Hard Rock Stadium
• Location: Miami Gardens, FL
• Time: Sunday 1:00 p.m. ET
• Spread: LAC -3.5 | Total: 43.5
• Moneyline: LAC -200 | MIA +170

More travel and an early start for the Chargers. That leaves an edge in backing the underdog hosts in this one.

Predicted Outcome: Dolphins 21 – Chargers 20

Dallas Cowboys vs. Carolina Panthers

• Stadium: Bank of America Stadium
• Location: Charlotte, NC
• Time: Sunday 1:00 p.m. ET
• Spread: DAL -3.5 | Total: 49.5
• Moneyline: DAL -175 | CAR +150

The Cowboys have exceeded modest expectations so far this season. Still, they come out flat versus the Panthers.

Predicted Outcome: Panthers 28 – Cowboys 20

New England Patriots vs. New Orleans Saints

• Stadium: Caesars Superdome
• Location: New Orleans, LA
• Time: Sunday 1:00 p.m. ET
• Spread: NE -3.5 | Total: 45.5
• Moneyline: NE -185 | NO +155

This is a classic letdown spot for the Pats. Nevertheless, the Saints won’t be marching over anyone on Sunday.

Predicted Outcome: Patriots 24 – Saints 20

Tennessee Titans vs. Las Vegas Raiders

• Stadium: Allegiant Stadium
• Location: Las Vegas, NV
• Time: Sunday 4:05 p.m. ET
• Spread: LV -3.5 | Total: 40.5
• Moneyline: LV -230 | TEN +195

The Raiders will be ready to defend their home turf against an uninspired Titans offense.

Predicted Outcome: Raiders 21 – Titans 10

San Francisco 49ers vs. Tampa Bay Buccaneers

• Stadium: Raymond James Stadium
• Location: Tampa, FL
• Time: Sunday 4:25 p.m. ET
• Spread: TB -3.5 | Total: 47.5
• Moneyline: TB -165 | SF +140

Expect another game-winning drive in the fourth quarter. Bucs salvage a defensive slugfest.

Predicted Outcome: Buccaneers 21 – 49ers 18

Cincinnati Bengals vs. Green Bay Packers

• Stadium: Lambeau Field
• Location: Green Bay, WI
• Time: Sunday 4:25 p.m. ET
• Spread: GB -14.5 | Total: 44.5
• Moneyline: GB -1600 | CIN +800

The Bengals reaching 17 points against the Packers’ defense will be considered a win.

Predicted Outcome: Packers 31 – Bengals 17

Detroit Lions vs. Kansas City Chiefs

• Stadium: Arrowhead Stadium
• Location: Kansas City, MO
• Time: Sunday 8:20 p.m. ET
• Spread: KC -1.5 | Total: 52.5
• Moneyline: KC -130 | DET +110

These teams will be ready to shoot out the lights. Advantage, Lions.

Predicted Outcome: Lions 38 – Chiefs 35

Buffalo Bills vs. Atlanta Falcons

• Stadium: Mercedes-Benz Stadium
• Location: Atlanta, GA
• Time: Monday 7:15 p.m. ET
• Spread: BUF -4.5 | Total: 49.5
• Moneyline: BUF -215 | ATL +180

The Falcons are rested and come out firing on all cylinders. Bills close late but come up short.

Predicted Outcome: Falcons 28 – Bills 24

Chicago Bears vs. Washington Commanders

• Stadium: Northwest Stadium
• Location: Landover, MD
• Time: Monday 8:15 p.m. ET
• Spread: WSH -4.5 | Total: 49.5
• Moneyline: WSH -230 | CHI +195

Commanders impose themselves on both sides of the football. A convincing victory.

Predicted Outcome: Commanders 33 – Bears 17

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