5 Underrated NFL Week 16 Favorites to Cover the Spread

Zack Cook
Host · Writer
Buffalo Bills (-12.5) vs. Los Angeles Chargers
The Buffalo Bills have strung together a pair of dominant victories over the Dallas Cowboys and Kansas City Chiefs. The Bills are putting the pieces together at the right time of year and are back in the playoff picture. Although this matchup has a prime letdown spot written all over it, it's hard to see the Los Angeles Chargers putting up much of a fight, even with a new coach. Even if the Bills don't have their best punch, we expect them to win by two touchdowns.
New Orleans Saints vs. Los Angeles Rams (-4.5)
The Los Angeles Rams and New Orleans Saints are coming off convincing wins in Week 15. They'll be colliding on Thursday Night Football, with the Rams listed as a 4.5-point home favorite. There's a lot to like about the Rams' depth on offense, especially with Kyren Williams carrying the workload in the backfield. We're not confident in the Saints to keep up offensively, thus liking the Rams to cover the number.
Arizona Cardinals vs. Chicago Bears (-4.5)
If there's one team to watch out for in 2024 after what we've seen from them in the back half of this season, it's the Chicago Bears. Defensively, this team has made strides, and there's a lot of positivity stemming from this franchise, with some high draft picks to utilize. It's hard to see the Cardinals running the ball well against this strong Bears defense, leading us to back Chicago to come out on top at home by a touchdown.
Cincinnati Bengals (-1.5) vs. Pittsburgh Steelers
If there's one team we've struggled to get right this season, it's consistently been the Pittsburgh Steelers. The Steelers have lost three in a row and have seen their playoff hopes flushed down the toilet. On the other hand, the Cincinnati Bengals have emerged in the race and sit in a playoff spot entering Week 16. The Bengals have positive momentum, and we don't like the way the Steelers have responded lately.
Green Bay Packers (-4.5) vs. Carolina Panthers
After pulling off a stunner in Week 13 against the Kansas City Chiefs, the Green Bay Packers have followed that up with losses to the New York Giants and Tampa Bay Buccaneers. The Packers now find themselves in a must-win situation on the road in Week 16, and we expect them to perform that way. Green Bay's defense is still a concern, but their offense will do enough to cover the number.
Buffalo Bills (-12.5) vs. Los Angeles Chargers
The Buffalo Bills have strung together a pair of dominant victories over the Dallas Cowboys and Kansas City Chiefs. The Bills are putting the pieces together at the right time of year and are back in the playoff picture. Although this matchup has a prime letdown spot written all over it, it's hard to see the Los Angeles Chargers putting up much of a fight, even with a new coach. Even if the Bills don't have their best punch, we expect them to win by two touchdowns.
New Orleans Saints vs. Los Angeles Rams (-4.5)
The Los Angeles Rams and New Orleans Saints are coming off convincing wins in Week 15. They'll be colliding on Thursday Night Football, with the Rams listed as a 4.5-point home favorite. There's a lot to like about the Rams' depth on offense, especially with Kyren Williams carrying the workload in the backfield. We're not confident in the Saints to keep up offensively, thus liking the Rams to cover the number.

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