NCAAF · 3 hours ago

Week 10 College Football Predictions for All 17 Top 25 Matchups

Grant White

Host · Writer

(17) Cincinnati Bearcats vs (24) Utah Utes
- Stadium: Rice-Eccles Stadium
- Location: Salt Lake City, UT
- Time: Saturday 10:15 p.m. ET
- Spread: UTAH -10.5 | Total: 54.5
- Moneyline: UTAH -360 | CIN +280
In no way, shape, or form is Utah this far ahead of Cincinnati. Bearcats pull off a stunner.

Predicted Outcome: Cincinnati 35 - Utah 31

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(25) Memphis Tigers vs Rice Owls
- Stadium: Rice Stadium
- Location: Houston, TX
- Time: Friday 7:00 p.m. ET
- Spread: MEM -13.5 | Total: 48.5
- Moneyline: MEM -650 | RICE +425
This is shaping up as a classic letdown spot for the Tigers. Still, Memphis prevails with a late score.

Predicted Outcome: Memphis 33 - Rice 27

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Penn State Nittany Lions vs (1) Ohio State Buckeyes
- Stadium: Ohio Stadium
- Location: Columbus, OH
- Time: Saturday 12:00 p.m. ET
- Spread: OSU -20.5 | Total: 44.5
- Moneyline: OSU -1800 | PSU +900
A few weeks ago, everyone was looking forward to this matchup. Now, it just feels like a formality.

Predicted Outcome: Ohio State 31 - Penn State 17
West Virginia Mountaineers vs (22) Houston Cougars
- Stadium: TDECU Stadium
- Location: Houston, TX
- Time: Saturday 12:00 p.m. ET
- Spread: HOU -12.5 | Total: 49.5
- Moneyline: HOU -550 | WVU +380
Houston is finally starting to get the respect it deserves. The Cougars' climb continues with a convincing win in Week 10.

Predicted Outcome: Houston 35 - West Virginia 13
(10) Miami (FL) Hurricanes vs SMU Mustangs
- Stadium: Gerald J. Ford Stadium
- Location: Dallas, TX
- Time: Saturday 12:00 p.m. ET
- Spread: MIA -11.5 | Total: 50.5
- Moneyline: MIA -450 | SMU +340
SMU will be ready to defend its home turf. This one will have Miami fans on edge.

Predicted Outcome: Miami 28 - SMU 27
(9) Vanderbilt Commodores vs (20) Texas Longhorns
- Stadium: DKR-Texas Memorial Stadium
- Location: Austin, TX
- Time: Saturday 12:00 p.m. ET
- Spread: TEX -2.5 | Total: 44.5
- Moneyline: TEX -135 | VAN +115
Nothing we've seen from Texas this season supports that they are worthy of this betting steam.

Predicted Outcome: Vanderbilt 23 - Texas 20

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(16) Louisville Cardinals vs Virginia Tech Hokies
- Stadium: Lane Stadium
- Location: Blacksburg, VA
- Time: Saturday 3:00 p.m. ET
- Spread: LOU -10.5 | Total: 53.5
- Moneyline: LOU -450 | VT +340
We still doubt the Cardinals, but we know Virginia Tech will let us down.

Predicted Outcome: Louisville 35 - Virginia Tech 24
(13) Texas Tech Red Raiders vs Kansas State Wildcats
- Stadium: Bill Snyder Family Stadium
- Location: Manhattan, KS
- Time: Saturday 3:30 p.m. ET
- Spread: TTU -7.5 | Total: 52.5
- Moneyline: TTU -280 | KSU +230
K-State is on the rise, but Texas Tech's offense proves to be too much.

Predicted Outcome: Texas Tech 42 - Kansas State 35
(12) Notre Dame Fighting Irish vs Boston College Eagles
- Stadium: Alumni Stadium
- Location: Chestnut Hill, MA
- Time: Saturday 3:30 p.m. ET
- Spread: ND -28.5 | Total: 56.5
- Moneyline: ND -7500 | BC +2000
Notre Dame has a path to the CFP, but it can't look past any of its opponents, starting with Boston College in Week 10.

Predicted Outcome: Notre Dame 56 - Boston College 10
(2) Indiana Hoosiers vs Maryland Terrapins
- Stadium: SECU Stadium
- Location: College Park, MD
- Time: Saturday 3:30 p.m. ET
- Spread: IU -21.5 | Total: 50.5
- Moneyline: IU -4000 | +1300
Maryland is completely outmatched on both sides of the football. Indiana cruises to a comfortable win.

Predicted Outcome: Indiana 42 - Maryland 21
(5) Georgia Bulldogs vs Florida Gators
- Stadium: EverBank Stadium
- Location: Jacksonville, FL
- Time: Saturday 3:30 p.m. ET
- Spread: UGA -7.5 | Total: 50.5
- Moneyline: UGA -290 | FLA +240
Georgia is in a tough spot on Saturday. We think the Bulldogs find a way to win, but the Gators keep things close.

Predicted Outcome: Georgia 21 - Florida 17
(15) Virginia Cavaliers vs California Golden Bears
- Stadium: California Memorial Stadium
- Location: Berkeley, CA
- Time: Saturday 3:45 p.m. ET
- Spread: UVA -4.5 | Total: 53.5
- Moneyline: UVA -190 | CAL +160
Virginia is on upset watch as they take on a Cal team that usually excels at home.

Predicted Outcome: California 21 - Virginia 18
South Carolina Gamecocks vs (7) Ole Miss Rebels
- Stadium: Vaught-Hemingway Stadium
- Location: Oxford, MS
- Time: Saturday 7:00 p.m. ET
- Spread: MISS -12.5 | Total: 55.5
- Moneyline: MISS -550 | SC +380
South Carolina emptied the tank last week and will come up empty-handed against Ole Miss.

Predicted Outcome: Ole Miss 31 - South Carolina 10
Purdue Boilermakers vs (21) Michigan Wolverines
- Stadium: Michigan Stadium
- Location: Ann Arbor, MI
- Time: Saturday 7:00 p.m. ET
- Spread: MICH -21.5 | Total: 49.5
- Moneyline: MICH -2000 | PUR +1000
Michigan needs a perfect end to the campaign, and the Wolverines have to take Purdue seriously.

Predicted Outcome: Michigan 31 - Purdue 13
(8) Georgia Tech Yellow Jackets vs North Carolina State Wolfpack
- Stadium: Wayne Day Family Field at Carter-Finley Stadium
- Location: Raleigh, NC
- Time: Saturday 7:30 p.m. ET
- Spread: GT -5.5 | Total: 58.5
- Moneyline: GT -225 | NCST +190
This has all the makings of a last-possession game. Nevertheless, Georgia Tech keeps its perfect season intact.

Predicted Outcome: Georgia Tech 34 - North Carolina State 31
(18) Oklahoma Sooners vs (14) Tennessee Volunteers
- Stadium: Neyland Stadium
- Location: Knoxville, TN
- Time: Saturday 7:30 p.m. ET
- Spread: TENN -3.5 | Total: 56.5
- Moneyline: TENN -140 | OKLA +120
It's time for Oklahoma to get real about its playoff chances. Tennessee in a romp.

Predicted Outcome: Tennessee 28 - Oklahoma 10
(23) USC Trojans vs Nebraska Cornhuskers
- Stadium: Memorial Stadium
- Location: Lincoln, NE
- Time: Saturday 7:30 p.m. ET
- Spread: USC -6.5 | Total: 58.5
- Moneyline: USC -240 | NEB +200
Nebraska's unflattering record versus ranked opponents comes to an end.

Predicted Outcome: Nebraska 31 - USC 28
(17) Cincinnati Bearcats vs (24) Utah Utes
- Stadium: Rice-Eccles Stadium
- Location: Salt Lake City, UT
- Time: Saturday 10:15 p.m. ET
- Spread: UTAH -10.5 | Total: 54.5
- Moneyline: UTAH -360 | CIN +280
In no way, shape, or form is Utah this far ahead of Cincinnati. Bearcats pull off a stunner.

Predicted Outcome: Cincinnati 35 - Utah 31

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(25) Memphis Tigers vs Rice Owls
- Stadium: Rice Stadium
- Location: Houston, TX
- Time: Friday 7:00 p.m. ET
- Spread: MEM -13.5 | Total: 48.5
- Moneyline: MEM -650 | RICE +425
This is shaping up as a classic letdown spot for the Tigers. Still, Memphis prevails with a late score.

Predicted Outcome: Memphis 33 - Rice 27

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Week 10 College Football Predictions for All 17 Top 25 Matchups

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