Louisville (-7.5) at Virginia - Saturday at 3:30 pm
The Virginia Cavaliers sitting at 4-1 after five games is a surprise to all but the most diehard college football fans. UVA beat Richmond, survived with a one-point win at Wake Forest and then impressed with wins at Coastal Carolina and Boston College last weekend. Virginia's only blemish is a 14-point defeat to Maryland.
Louisville was considered a threat to win the ACC but they have blown chances to impress each of the past two weeks, losing to Notre Dame and SMU. The defense just has not performed as well as fans had hoped and this game falls at a very perilous time for the Cardinals. Louisville has lost two straight and hosts Miami next Saturday before three straight road games (BC, Clemson, Stanford). If Louisville looks ahead to the Hurricanes whatsoever, Virginia has enough firepower to punish them.